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ABI1 and PCM1
Data Source:
BioGRID
(two hybrid)
ABI1
PCM1
Description
abl interactor 1
pericentriolar material 1
Image
No pdb structure
GO Annotations
Cellular Component
Intracellular Anatomical Structure
Nucleus
Endoplasmic Reticulum
Cytosol
Cytoskeleton
Postsynaptic Density
Lamellipodium
Growth Cone
SCAR Complex
Filopodium Tip
Extracellular Exosome
Pericentriolar Material
Cytoplasm
Centrosome
Centriole
Cytosol
Membrane
Nuclear Membrane
Protein-containing Complex
Centriolar Satellite
Ciliary Transition Zone
Ciliary Basal Body
Apical Part Of Cell
Non-motile Cilium
Molecular Function
Protein Binding
Cytoskeletal Protein Binding
SH3 Domain Binding
Protein Tyrosine Kinase Activator Activity
Signaling Adaptor Activity
Cadherin Binding
Protein Binding
Identical Protein Binding
Biological Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Actin Polymerization Or Depolymerization
Negative Regulation Of Cell Population Proliferation
Viral Process
Peptidyl-tyrosine Phosphorylation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Protein Tyrosine Kinase Activity
G2/M Transition Of Mitotic Cell Cycle
Neuron Migration
Centrosome Cycle
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Interkinetic Nuclear Migration
Cytoplasmic Microtubule Organization
Microtubule Anchoring
Microtubule Anchoring At Centrosome
Social Behavior
Intraciliary Transport Involved In Cilium Assembly
Negative Regulation Of Neurogenesis
Cilium Assembly
Protein Localization To Centrosome
Positive Regulation Of Intracellular Protein Transport
Neuronal Stem Cell Population Maintenance
Ciliary Basal Body-plasma Membrane Docking
Non-motile Cilium Assembly
Pathways
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
VEGFA-VEGFR2 Pathway
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Atrial fibrillation (
28416818
)
Economic and political preferences (
22566634
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) (
26503814
)
Triglyceride levels (
32203549
)
Waist-hip ratio (
30108283
)
Weight (
28552196
)
Interacting Genes
64 interacting genes:
ABI2
ABL1
APBB1
C22orf15
CACNA1A
CCDC57
CCHCR1
CYFIP2
DST
DTNB
EIF3H
ENAH
ENKD1
EPS8
EPS8L1
EVL
FAM124B
FBXL19
FHL2
GAS7
HHEX
HNRNPK
HOMER1
HOMER3
HSPA8
KIAA0408
KIAA1217
KTN1
LMO1
MAB21L2
MINK1
MRFAP1
MRFAP1L1
NCK1
NCK2
NCKAP1
NEB
NFASC
NHSL2
NIN
PAK2
PCM1
PRKAA2
PRPF40A
RBM15
RCOR3
SMARCD1
SORBS1
SORBS2
SOS1
SOS2
SPTA1
SPTAN1
SRP68
SRRM1
SYNE2
TCERG1
TLN1
TRIP10
TTC23
VARS2
VASP
WASF1
WASF2
43 interacting genes:
ABI1
ABI2
AKAP9
BBS4
CASK
CCDC172
CCHCR1
CDC42
CEP72
CYTH4
DDIT3
DDX23
DYNLL1
E2F4
ECPAS
EPS8
EXOC8
FAM81A
FXR2
GABARAP
GOLGA2
HAP1
ING5
KLC1
KLC4
KRT15
KRT19
KRT24
MCRS1
NDC80
NECAB2
PCNT
PRC1
PRKCI
RALBP1
RBM5
RINT1
RPA2
TFIP11
TTC8
WASHC3
YWHAE
YWHAQ
Entrez ID
10006
5108
HPRD ID
04336
02624
Ensembl ID
ENSG00000136754
ENSG00000078674
Uniprot IDs
A0A0A0MRT6
B6VEX3
B6VEX4
B6VEX5
Q8IZP0
A2RUU9
B9EIS5
Q15154
PDB IDs
6HYL
6HYM
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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