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USP13

Description ubiquitin specific peptidase 13
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytosol
Molecular Function
  • Cysteine-type Endopeptidase Activity
  • Thiol-dependent Ubiquitin-specific Protease Activity
  • Protein Binding
  • Zinc Ion Binding
  • Ubiquitin Protein Ligase Binding
  • Ubiquitin Binding
  • Ubiquitin-like Protein Ligase Binding
  • Chaperone Binding
  • Proteasome Binding
  • BAT3 Complex Binding
  • Lys48-specific Deubiquitinase Activity
Biological Process
  • Regulation Of Transcription, DNA-templated
  • Ubiquitin-dependent Protein Catabolic Process
  • Autophagy
  • Cell Population Proliferation
  • Regulation Of Autophagy
  • Protein Deubiquitination
  • Protein Phosphopantetheinylation
  • Melanocyte Differentiation
  • Protein K29-linked Deubiquitination
  • Protein K6-linked Deubiquitination
  • Protein Stabilization
  • Protein K63-linked Deubiquitination
  • Protein K48-linked Deubiquitination
  • Positive Regulation Of ERAD Pathway
  • Maintenance Of Unfolded Protein Involved In ERAD Pathway
Pathways
  • Ub-specific processing proteases
  • Regulation of PTEN stability and activity
Drugs
Diseases
GWAS
Novel Interacting Genes 5 novel interacting genes: GPR160 HSP90AA1 S100A9 SYCP2 TRA2B
Interacting Genes 18 interacting genes: AMFR BAG6 DAZAP2 DVL1 FNBP1L FUNDC2 LAPTM5 MCL1 MDC1 MRPL20 MYO15A SIAH2 SPRR2C TRIM55 TRIM63 UBC UBL4A UIMC1
Entrez ID 8975
HPRD ID 04666
Ensembl ID ENSG00000058056
Uniprot IDs A0A0A6YZ17 Q92995
PDB IDs 2L80 2LBC
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025