RAG2

Description		recombination activating 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm DNA Recombinase Complex
	Molecular Function	Chromatin Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Zinc Ion Binding Methylated Histone Binding Phosphatidylinositol Binding Phosphatidylinositol-3,4-bisphosphate Binding Sequence-specific DNA Binding Ubiquitin Protein Ligase Activity Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	B Cell Lineage Commitment Pre-B Cell Allelic Exclusion B Cell Homeostatic Proliferation T Cell Lineage Commitment Chromatin Organization Protein Ubiquitination B Cell Differentiation T Cell Differentiation In Thymus V(D)J Recombination Defense Response To Bacterium Positive Regulation Of Organ Growth
Pathways		Interleukin-7 signaling MAPK6/MAPK4 signaling
Drugs
Diseases		Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency T-B-Severe combined immunodeficiencies (SCIDs), including the following four diseases: Adenosine deaminase (ADA) deficiency; Recombinase activating gene (RAG) deficiencies; Artemis deficiency; Reticular dysgenesis
GWAS		Rheumatoid arthritis ( 24390342)
Novel Interacting Genes		3 novel interacting genes: CAPRIN1 LMO2 RCN1
Interacting Genes		3 interacting genes: IPO5 RAG1 SKP2
Entrez ID		5897
HPRD ID		08913
Ensembl ID		ENSG00000175097
Uniprot IDs		P55895
PDB IDs
Enriched GO Terms of Interacting Partners?
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