RAG2 and CAPRIN1

Data Source:
BioGRID (proximity labelling technology)

		RAG2	CAPRIN1
Description		recombination activating 2	cell cycle associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm DNA Recombinase Complex	P-body Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane Lamellipodium Dendrite Cell Leading Edge Synapse
	Molecular Function	Chromatin Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Zinc Ion Binding Methylated Histone Binding Phosphatidylinositol Binding Phosphatidylinositol-3,4-bisphosphate Binding Sequence-specific DNA Binding Ubiquitin Protein Ligase Activity Phosphatidylinositol-3,5-bisphosphate Binding	RNA Binding Protein Binding
	Biological Process	B Cell Lineage Commitment Pre-B Cell Allelic Exclusion B Cell Homeostatic Proliferation T Cell Lineage Commitment Chromatin Organization Protein Ubiquitination B Cell Differentiation T Cell Differentiation In Thymus V(D)J Recombination Defense Response To Bacterium Positive Regulation Of Organ Growth	Negative Regulation Of Translation Positive Regulation Of Dendrite Morphogenesis Positive Regulation Of Dendritic Spine Morphogenesis
Pathways		Interleukin-7 signaling MAPK6/MAPK4 signaling
Drugs
Diseases		Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency T-B-Severe combined immunodeficiencies (SCIDs), including the following four diseases: Adenosine deaminase (ADA) deficiency; Recombinase activating gene (RAG) deficiencies; Artemis deficiency; Reticular dysgenesis
GWAS		Rheumatoid arthritis ( 24390342)	Coronary atherosclerosis (increased number of diseased vessels) (traffic exposure interaction) ( 28355232) Iron status biomarkers (transferrin saturation) ( 28334935) Systolic blood pressure ( 30224653)
Interacting Genes		3 interacting genes: IPO5 RAG1 SKP2	6 interacting genes: APP DAPK1 MFHAS1 PIN1 PRMT1 WBP4
Entrez ID		5897	4076
HPRD ID		08913	03108
Ensembl ID		ENSG00000175097	ENSG00000135387
Uniprot IDs		P55895	Q14444
PDB IDs			4WBE 4WBP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?