RAG2 and RCN1

Data Source:
BioGRID (two hybrid)

		RAG2	RCN1
Description		recombination activating 2	reticulocalbin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm DNA Recombinase Complex	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Chromatin Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Zinc Ion Binding Methylated Histone Binding Phosphatidylinositol Binding Phosphatidylinositol-3,4-bisphosphate Binding Sequence-specific DNA Binding Ubiquitin Protein Ligase Activity Phosphatidylinositol-3,5-bisphosphate Binding	Calcium Ion Binding Protein Binding
	Biological Process	B Cell Lineage Commitment Pre-B Cell Allelic Exclusion B Cell Homeostatic Proliferation T Cell Lineage Commitment Chromatin Organization Protein Ubiquitination B Cell Differentiation T Cell Differentiation In Thymus V(D)J Recombination Defense Response To Bacterium Positive Regulation Of Organ Growth	In Utero Embryonic Development Camera-type Eye Development Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Interleukin-7 signaling MAPK6/MAPK4 signaling	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases		Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency T-B-Severe combined immunodeficiencies (SCIDs), including the following four diseases: Adenosine deaminase (ADA) deficiency; Recombinase activating gene (RAG) deficiencies; Artemis deficiency; Reticular dysgenesis
GWAS		Rheumatoid arthritis ( 24390342)	Apolipoprotein B levels ( 32203549) Basophil count ( 32888494) Blood protein levels ( 30072576) Body mass index ( 28371326) General factor of neuroticism ( 30867560) Major depressive disorder ( 27479909) Metabolite levels (HVA/5-HIAA ratio) ( 23319000) Refractive error ( 32231278)
Interacting Genes		3 interacting genes: IPO5 RAG1 SKP2	19 interacting genes: ASB8 ASPH ATPAF2 ATXN1 CETN3 DCAF11 EFHC1 ENKD1 FAM110A GADD45G LMO1 LMO2 LMO3 LMO4 MYO15B PTEN SGTA SGTB ZNF410
Entrez ID		5897	5954
HPRD ID		08913	04111
Ensembl ID		ENSG00000175097	ENSG00000049449
Uniprot IDs		P55895	Q15293 V9HW95
PDB IDs
Enriched GO Terms of Interacting Partners?
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