NDST1

Description		N-deacetylase and N-sulfotransferase 1
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GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Protein Binding [heparan Sulfate]-glucosamine N-sulfotransferase Activity Deacetylase Activity Heparan Sulfate N-deacetylase Activity
	Biological Process	Cardiac Septum Development Glycosaminoglycan Biosynthetic Process Protein Sulfation Inflammatory Response Respiratory Gaseous Exchange By Respiratory System Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Heparan Sulfate Proteoglycan Biosynthetic Process, Polysaccharide Chain Biosynthetic Process Heparin Biosynthetic Process Forebrain Development Midbrain Development Aorta Development Positive Regulation Of MAPK Cascade Positive Regulation Of Smoothened Signaling Pathway Embryonic Neurocranium Morphogenesis Embryonic Viscerocranium Morphogenesis Coronary Vasculature Development
Pathways		HS-GAG biosynthesis
Drugs		Adenosine 3',5'-diphosphate
Diseases
GWAS		Blood protein levels ( 30072576) Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Neutrophil count ( 32888494)
Novel Interacting Genes		7 novel interacting genes: ABLIM3 ADAM18 CAMK2A HMGXB3 ITGA11 ST6GALNAC1 SYNPO
Interacting Genes
Entrez ID		3340
HPRD ID		02912
Ensembl ID		ENSG00000070614
Uniprot IDs		A8K8T3 B7Z1Q0 E7EVJ3 P52848
PDB IDs		1NST
Enriched GO Terms of Interacting Partners?
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