NDST1 and ITGA11

Data Source:
HPRD (in vitro)

		NDST1	ITGA11
Description		N-deacetylase and N-sulfotransferase 1	integrin subunit alpha 11
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane	Plasma Membrane Focal Adhesion Integrin Complex Membrane Integrin Alpha11-beta1 Complex
	Molecular Function	Protein Binding [heparan Sulfate]-glucosamine N-sulfotransferase Activity Deacetylase Activity Heparan Sulfate N-deacetylase Activity	Collagen Binding Collagen Receptor Activity Metal Ion Binding Collagen Binding Involved In Cell-matrix Adhesion
	Biological Process	Cardiac Septum Development Glycosaminoglycan Biosynthetic Process Protein Sulfation Inflammatory Response Respiratory Gaseous Exchange By Respiratory System Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Heparan Sulfate Proteoglycan Biosynthetic Process, Polysaccharide Chain Biosynthetic Process Heparin Biosynthetic Process Forebrain Development Midbrain Development Aorta Development Positive Regulation Of MAPK Cascade Positive Regulation Of Smoothened Signaling Pathway Embryonic Neurocranium Morphogenesis Embryonic Viscerocranium Morphogenesis Coronary Vasculature Development	Osteoblast Differentiation Substrate-dependent Cell Migration Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Muscle Organ Development Extracellular Matrix Organization Cell Adhesion Mediated By Integrin Collagen-activated Signaling Pathway
Pathways		HS-GAG biosynthesis	Integrin cell surface interactions Integrin cell surface interactions
Drugs		Adenosine 3',5'-diphosphate
Diseases
GWAS		Blood protein levels ( 30072576) Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Neutrophil count ( 32888494)	Attention deficit hyperactivity disorder ( 18839057) Dupuytren's disease ( 28886342) Major depressive disorder ( 23377640) Perceived intensity of fructose ( 31005972) Systolic blood pressure ( 26969751)
Interacting Genes			1 interacting genes: ITGB1
Entrez ID		3340	22801
HPRD ID		02912	05310
Ensembl ID		ENSG00000070614	ENSG00000137809
Uniprot IDs		A8K8T3 B7Z1Q0 E7EVJ3 P52848	B3KTN6 Q9UKX5
PDB IDs		1NST
Enriched GO Terms of Interacting Partners?
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