NDST1 and ADAM18

Data Source:
BioGRID (two hybrid)

		NDST1	ADAM18
Description		N-deacetylase and N-sulfotransferase 1	ADAM metallopeptidase domain 18
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane	Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding [heparan Sulfate]-glucosamine N-sulfotransferase Activity Deacetylase Activity Heparan Sulfate N-deacetylase Activity	Metalloendopeptidase Activity Metallopeptidase Activity
	Biological Process	Cardiac Septum Development Glycosaminoglycan Biosynthetic Process Protein Sulfation Inflammatory Response Respiratory Gaseous Exchange By Respiratory System Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Heparan Sulfate Proteoglycan Biosynthetic Process, Polysaccharide Chain Biosynthetic Process Heparin Biosynthetic Process Forebrain Development Midbrain Development Aorta Development Positive Regulation Of MAPK Cascade Positive Regulation Of Smoothened Signaling Pathway Embryonic Neurocranium Morphogenesis Embryonic Viscerocranium Morphogenesis Coronary Vasculature Development	Proteolysis Cell Adhesion Multicellular Organism Development Spermatogenesis Binding Of Sperm To Zona Pellucida Cell Differentiation
Pathways		HS-GAG biosynthesis
Drugs		Adenosine 3',5'-diphosphate
Diseases
GWAS		Blood protein levels ( 30072576) Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Neutrophil count ( 32888494)	HIV-1 susceptibility ( 22174851) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 26480920)
Interacting Genes
Entrez ID		3340	8749
HPRD ID		02912	07469
Ensembl ID		ENSG00000070614	ENSG00000168619
Uniprot IDs		A8K8T3 B7Z1Q0 E7EVJ3 P52848	Q0VAI3 Q9Y3Q7
PDB IDs		1NST
Enriched GO Terms of Interacting Partners?
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