NDST1 and ST6GALNAC1

Data Source:
HPRD (in vitro, in vivo)

		NDST1	ST6GALNAC1
Description		N-deacetylase and N-sulfotransferase 1	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane	Golgi Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding [heparan Sulfate]-glucosamine N-sulfotransferase Activity Deacetylase Activity Heparan Sulfate N-deacetylase Activity	Alpha-N-acetylgalactosaminide Alpha-2,6-sialyltransferase Activity Sialyltransferase Activity
	Biological Process	Cardiac Septum Development Glycosaminoglycan Biosynthetic Process Protein Sulfation Inflammatory Response Respiratory Gaseous Exchange By Respiratory System Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Heparan Sulfate Proteoglycan Biosynthetic Process, Polysaccharide Chain Biosynthetic Process Heparin Biosynthetic Process Forebrain Development Midbrain Development Aorta Development Positive Regulation Of MAPK Cascade Positive Regulation Of Smoothened Signaling Pathway Embryonic Neurocranium Morphogenesis Embryonic Viscerocranium Morphogenesis Coronary Vasculature Development	Protein Glycosylation Oligosaccharide Biosynthetic Process Sialylation
Pathways		HS-GAG biosynthesis	Sialic acid metabolism
Drugs		Adenosine 3',5'-diphosphate
Diseases
GWAS		Blood protein levels ( 30072576) Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Neutrophil count ( 32888494)
Interacting Genes			1 interacting genes: EXOSC2
Entrez ID		3340	55808
HPRD ID		02912	15340
Ensembl ID		ENSG00000070614	ENSG00000070526
Uniprot IDs		A8K8T3 B7Z1Q0 E7EVJ3 P52848	Q9NSC7
PDB IDs		1NST
Enriched GO Terms of Interacting Partners?
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