MIB2

Description		MIB E3 ubiquitin protein ligase 2
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Early Endosome Cytosol
	Molecular Function	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Notch Signaling Pathway Protein Ubiquitination Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways		Activated NOTCH1 Transmits Signal to the Nucleus Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants NOTCH2 Activation and Transmission of Signal to the Nucleus NOTCH3 Activation and Transmission of Signal to the Nucleus Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Body mass index ( 26426971) Height ( 31562340) Iris color (a* coordinate) ( 30895295) Iris color (b* coordinate) ( 30895295)
Novel Interacting Genes		2 novel interacting genes: DNAH7 PUSL1
Interacting Genes		10 interacting genes: ACTA1 ACTC1 BCL10 GRIN2B JAG2 SRPK2 TBK1 UBE2D2 UBE2N UBE2U
Entrez ID		142678
HPRD ID		15905
Ensembl ID		ENSG00000197530
Uniprot IDs		Q96AX9
PDB IDs
Enriched GO Terms of Interacting Partners?
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