NDUFAF2 and SMIM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NDUFAF2	SMIM1
Description		NADH:ubiquinone oxidoreductase complex assembly factor 2	small integral membrane protein 1 (Vel blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane	Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Protein Binding Protein-containing Complex Binding	Protein Binding Protein Homodimerization Activity
	Biological Process	Mitochondrial Respiratory Chain Complex I Assembly Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Pathways		Complex I biogenesis
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical surface area (MOSTest) ( 32665545) Cortical volume ( 32963231) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Parkinson's disease ( 27182965) Subcortical volume (MOSTest) ( 32665545)	Glycated hemoglobin levels ( 34059833) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		13 interacting genes: C5orf64 CYB5B GNL3LP1 ISCA1P1 LAT LPAR3 SEC22B SLC30A5 SMIM1 SPG21 STX8 TMEM201 TMEM97	56 interacting genes: ANKS6 AQP6 ASZ1 BCL2L13 BIK CD74 CISD2 COMT CREB3L1 CYB561 EBP ERGIC3 FAM174A FAM209A FAM210B FCER1G FFAR2 FNDC9 GJA8 GJB5 HACD2 HSD17B13 ICAM3 JAGN1 KIR2DL3 LHFPL5 LRP10 LRRC4C MFF MFSD6 MUC1 NAALAD2 NDUFAF2 PVR REEP4 RELL2 RETREG3 SAR1A SCN3B SDC3 SIGLEC7 SLC10A6 SLC18A1 SLC26A11 STING1 STX1A TM4SF19 TMEM154 TMEM31 TMEM45B TMEM51 TMEM52B TMEM86B TMPRSS2 TMX2 ZDHHC15
Entrez ID		91942	388588
HPRD ID		14288
Ensembl ID		ENSG00000164182	ENSG00000235169
Uniprot IDs		A0A0S2Z5U1 Q8N183	B2RUZ4 M4WDD3
PDB IDs
Enriched GO Terms of Interacting Partners?
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