NDUFAF2 and LPAR3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NDUFAF2	LPAR3
Description		NADH:ubiquinone oxidoreductase complex assembly factor 2	lysophosphatidic acid receptor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Axon Synapse
	Molecular Function	Protein Binding Protein-containing Complex Binding	G-protein Alpha-subunit Binding G Protein-coupled Receptor Activity Protein Binding Phospholipid Binding Lipid Binding Lysophosphatidic Acid Receptor Activity
	Biological Process	Mitochondrial Respiratory Chain Complex I Assembly Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus	G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Chemical Synaptic Transmission Regulation Of Metabolic Process Bleb Assembly Positive Regulation Of MAPK Cascade Positive Regulation Of Collateral Sprouting Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Positive Regulation Of Calcium Ion Transport
Pathways		Complex I biogenesis	G alpha (q) signalling events G alpha (i) signalling events Lysosphingolipid and LPA receptors
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical surface area (MOSTest) ( 32665545) Cortical volume ( 32963231) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Parkinson's disease ( 27182965) Subcortical volume (MOSTest) ( 32665545)	Cerebrospinal fluid t-tau:AB1-42 ratio ( 28641921) Dental caries ( 23064961) Glucose homeostasis traits ( 25524916) Heel bone mineral density ( 30598549) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)
Interacting Genes		13 interacting genes: C5orf64 CYB5B GNL3LP1 ISCA1P1 LAT LPAR3 SEC22B SLC30A5 SMIM1 SPG21 STX8 TMEM201 TMEM97	58 interacting genes: APP AQP6 ARL13B ASZ1 BCL2L13 C16orf54 CD53 CD74 CD79A CLDN2 CLDN7 CLDN9 CLEC12B CPLX4 CREB3L1 CYB561 CYBRD1 EDA ERGIC3 FAM209A FAM210B FFAR2 FNDC9 GJB5 GNAI2 GORAB GPX8 JAGN1 KCNC1 KCNJ6 LEPROTL1 LHFPL5 LIME1 LMNA MFF MGST3 MRM1 MS4A4A NDUFAF2 OPRM1 PGRMC2 RELL2 RETREG3 SCN3B SGMS2 SHISAL1 SLC10A6 SLC16A2 SLC35C2 TFEC THAP4 TMEM14B TMEM237 TMEM31 TMEM41A TMEM52B TMEM70 TMEM79
Entrez ID		91942	23566
HPRD ID		14288	05486
Ensembl ID		ENSG00000164182	ENSG00000171517
Uniprot IDs		A0A0S2Z5U1 Q8N183	Q9UBY5
PDB IDs
Enriched GO Terms of Interacting Partners?
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