NDUFAF2 and TMEM97

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NDUFAF2	TMEM97
Description		NADH:ubiquinone oxidoreductase complex assembly factor 2	transmembrane protein 97
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane	Lysosome Endoplasmic Reticulum Rough Endoplasmic Reticulum Plasma Membrane Integral Component Of Membrane Rough Endoplasmic Reticulum Membrane Nuclear Membrane
	Molecular Function	Protein Binding Protein-containing Complex Binding	Protein Binding
	Biological Process	Mitochondrial Respiratory Chain Complex I Assembly Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus	Regulation Of Cell Growth Cholesterol Homeostasis
Pathways		Complex I biogenesis
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical surface area (MOSTest) ( 32665545) Cortical volume ( 32963231) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Parkinson's disease ( 27182965) Subcortical volume (MOSTest) ( 32665545)	Advanced age-related macular degeneration ( 26691988) Blood protein levels ( 29875488) Osteoprotegerin levels ( 25080503)
Interacting Genes		13 interacting genes: C5orf64 CYB5B GNL3LP1 ISCA1P1 LAT LPAR3 SEC22B SLC30A5 SMIM1 SPG21 STX8 TMEM201 TMEM97	70 interacting genes: ADCYAP1R1 APP AQP12B AQP2 AQP6 ARL13B ASZ1 ATP6AP2 BCL2L13 BIK CD53 CD74 CGRRF1 CLDN7 CLSTN3 CPLX4 CRLF3 EBP ERAL1 ERGIC3 FAM209A FFAR2 FKBP7 FRMD3 FXYD3 GJB3 GJB5 GPR152 GPR37L1 GPX8 HSD17B13 IFNGR2 KIR2DL3 LEUTX LHFPL5 LIME1 LRRC59 MFF MRM1 MTIF3 MUC1 NDUFAF1 NDUFAF2 NEMP1 ORC1 PDCD1LG2 PDZK1IP1 PLP1 POLDIP2 PSCA REEP1 RHCG RNF167 RNF170 SAR1A SGPL1 SLC14A1 SLC14A2 SPINT1 SSMEM1 TADA1 TBC1D29P TMEM106C TMEM14B TMEM45B TMEM52B TMEM79 TMX2 UTP4 VSIR
Entrez ID		91942	27346
HPRD ID		14288	14343
Ensembl ID		ENSG00000164182	ENSG00000109084
Uniprot IDs		A0A0S2Z5U1 Q8N183	Q5BJF2
PDB IDs
Enriched GO Terms of Interacting Partners?
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