SMIM1 and ANKS6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SMIM1	ANKS6
Description		small integral membrane protein 1 (Vel blood group)	ankyrin repeat and sterile alpha motif domain containing 6
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane	Cytoplasm Ciliary Inversin Compartment
	Molecular Function	Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process		In Utero Embryonic Development Kidney Development Determination Of Left/right Symmetry Heart Development
Pathways
Drugs
Diseases
GWAS		Glycated hemoglobin levels ( 34059833) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Body mass index ( 28892062)
Interacting Genes		56 interacting genes: ANKS6 AQP6 ASZ1 BCL2L13 BIK CD74 CISD2 COMT CREB3L1 CYB561 EBP ERGIC3 FAM174A FAM209A FAM210B FCER1G FFAR2 FNDC9 GJA8 GJB5 HACD2 HSD17B13 ICAM3 JAGN1 KIR2DL3 LHFPL5 LRP10 LRRC4C MFF MFSD6 MUC1 NAALAD2 NDUFAF2 PVR REEP4 RELL2 RETREG3 SAR1A SCN3B SDC3 SIGLEC7 SLC10A6 SLC18A1 SLC26A11 STING1 STX1A TM4SF19 TMEM154 TMEM31 TMEM45B TMEM51 TMEM52B TMEM86B TMPRSS2 TMX2 ZDHHC15	20 interacting genes: AGTRAP APP BCL2L2 BET1 C1GALT1 C5 EMD EMP1 IGFBP5 MARCHF5 MFSD14C PITPNC1 RTP2 SMIM1 STRIT1 STX7 TMEM120B TMEM60 VAMP4 VEZT
Entrez ID		388588	203286
HPRD ID			18012
Ensembl ID		ENSG00000235169	ENSG00000165138
Uniprot IDs		B2RUZ4 M4WDD3	B3KXP1 Q68DC2
PDB IDs			4NL9
Enriched GO Terms of Interacting Partners?
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