SMIM1 and SLC18A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SMIM1	SLC18A1
Description		small integral membrane protein 1 (Vel blood group)	solute carrier family 18 member A1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane	Endoplasmic Reticulum Membrane Integral Component Of Membrane Synaptic Vesicle Membrane Terminal Bouton Clathrin-sculpted Monoamine Transport Vesicle Membrane
	Molecular Function	Protein Binding Protein Homodimerization Activity	Serotonin:sodium Symporter Activity Monoamine Transmembrane Transporter Activity Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity
	Biological Process		Aminergic Neurotransmitter Loading Into Synaptic Vesicle Monoamine Transport Xenobiotic Transport Serotonin Uptake Transmembrane Transport
Pathways			Na+/Cl- dependent neurotransmitter transporters
Drugs			Reserpine Norepinephrine Ephedra sinica root MMDA Metamfetamine
Diseases
GWAS		Glycated hemoglobin levels ( 34059833) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Apolipoprotein A1 levels ( 32203549) Cholesterol ( 31902109) Coronary artery disease ( 30104761) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol levels ( 32203549) Hypertriglyceridemia ( 23505323) Major depressive disorder (broad) ( 20038947) Metabolic syndrome ( 30382898 31589552) Persistent hepatitis B virus infection ( 27244555) Pulse pressure ( 27841878) Response to selenium supplementation (change in plasma selenium concentration) ( 33382417) Systolic blood pressure ( 27841878) Triglyceride levels ( 32203549) Triglyceride levels in HIV infection ( 33109212) Triglycerides ( 18193046 24886709)
Interacting Genes		56 interacting genes: ANKS6 AQP6 ASZ1 BCL2L13 BIK CD74 CISD2 COMT CREB3L1 CYB561 EBP ERGIC3 FAM174A FAM209A FAM210B FCER1G FFAR2 FNDC9 GJA8 GJB5 HACD2 HSD17B13 ICAM3 JAGN1 KIR2DL3 LHFPL5 LRP10 LRRC4C MFF MFSD6 MUC1 NAALAD2 NDUFAF2 PVR REEP4 RELL2 RETREG3 SAR1A SCN3B SDC3 SIGLEC7 SLC10A6 SLC18A1 SLC26A11 STING1 STX1A TM4SF19 TMEM154 TMEM31 TMEM45B TMEM51 TMEM52B TMEM86B TMPRSS2 TMX2 ZDHHC15	61 interacting genes: AGTRAP ANKRD46 APOL2 BRICD5 C2CD2L CCL4 CCL4L2 CNIH1 COL4A5 CTSA CXCL16 CYB561D2 FAM3C FCER1G FXYD3 GIMAP1 GJB2 GPR151 LAT MALL MFSD6 MGAM MIP MS4A1 MS4A13 NEU1 NRM OLFM4 ORMDL1 PEX16 PLP1 PLP2 PMP22 PNLIPRP1 PPP3CC RPRM SLC30A2 SLC30A8 SLC35B4 SLC35G1 SLC38A7 SLC39A2 SMCO4 SMIM1 STX2 STX8 TFRC TMEM120B TMEM128 TMEM14A TMEM14B TMEM203 TMEM218 TMEM239 TMEM42 TMEM60 TMEM65 TMEM86A VAMP5 YIPF4 YIPF6
Entrez ID		388588	6570
HPRD ID			01897
Ensembl ID		ENSG00000235169	ENSG00000036565
Uniprot IDs		B2RUZ4 M4WDD3	P54219 Q96GL6
PDB IDs
Enriched GO Terms of Interacting Partners?
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