CUL4B and AMBRA1

  • Number of citations of the paper that reports this interaction (PubMedID 31973889)
  • 8
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

CUL4B

AMBRA1

Description cullin 4B autophagy and beclin 1 regulator 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 28552196)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597)
  • Immunoglobulin A ( 20694011)
  • Insulin-related traits (multivariate analysis) ( 32002517)
  • Normal facial asymmetry (angle of deformation score) ( 30631343)
  • Schizophrenia ( 28991256 29483656 30285260)
  • Selective IgA deficiency ( 27723758)
Interacting Genes 55 interacting genes: AHR AMBRA1 APP AR BRWD1 BRWD3 CAND1 COMMD1 COP1 COPS2 COPS5 CRBN CUL4A DCAF10 DCAF11 DCAF12 DCAF15 DCAF16 DCAF17 DCAF4 DCAF5 DCAF6 DCUN1D1 DCUN1D4 DDA1 DDB1 DDB2 DET1 DNMT3B DTL ERCC8 ESR1 GLMN HUWE1 KPNA2 KPNA4 KPNB1 NEDD8 PHIP PLS3 PRDX3 PTEN PWP1 RBX1 RNF7 SALL2 SIN3A SRC ST7 TBL3 TRPC4AP UBC UBE2D3 WDTC1 ZMAT4 20 interacting genes: ALX4 BECN1 CHUK CREM CUL4B GABARAP GABARAPL1 GABARAPL2 HSD17B12 KBTBD4 MAP1LC3A MAP1LC3B MAP1LC3C MTCH2 MTOR PEX11A RNF2 SLC35C1 SNCA UBE2D3
Entrez ID 8450 55626
HPRD ID 02251 10975
Ensembl ID ENSG00000158290 ENSG00000110497
Uniprot IDs K4DI93 Q13620 A0A075B6T1 Q9C0C7
PDB IDs 2DO7 4A0C 4A0L 4A64
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?