CCDC102B and PFKFB4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CCDC102B	PFKFB4
Description		coiled-coil domain containing 102B	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytosol
	Molecular Function	Protein Binding	6-phosphofructo-2-kinase Activity Fructose-2,6-bisphosphate 2-phosphatase Activity Protein Binding ATP Binding
	Biological Process		Fructose Metabolic Process Fructose 2,6-bisphosphate Metabolic Process Dephosphorylation Carbohydrate Phosphorylation
Pathways			Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
Drugs			Phosphoaminophosphonic Acid-Adenylate Ester Fructose-6-phosphate
Diseases
GWAS		Caudate activity during reward ( 28927378) Liver enzyme levels (alanine transaminase) ( 24124411) Myopic maculopathy ( 29725004) Pursuit maintenance gain ( 29064472) Pursuit maintenance gain in psychotic disorders ( 29064472) Rostral anterior cingulate cortex volume ( 31530798)	Bitter beverage consumption ( 31046077) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Mental health study participation (completed survey) ( 31263887) Morning person ( 30696823) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908 25082827) Waist-hip index ( 34021172)
Interacting Genes		102 interacting genes: ABI2 AK8 ANKRD23 ARL4A ARL4D BYSL C20orf202 CACNB4 CAPN3 CCDC120 CCDC187 CCDC33 CCHCR1 CDK18 CEP19 CEP57L1 CWF19L2 DISC1 DOCK10 EFHC2 EHHADH ENKD1 EXOC5 FAM161A FAM217B FBF1 FH FLOT1 FNDC11 GEM GOPC HMG20B IKZF3 KIFC3 KPNA3 KRT75 KRTAP13-3 LENG1 LMO4 LNX1 LZTS1 MAB21L2 MAGOHB MARK1 MCM7 MEOX1 MEOX2 MFAP1 MOS MSX2 NIF3L1 NME4 NTAQ1 NXT2 PFKFB4 PHAF1 PICK1 PNMA5 POMC POP5 PPP1R13B PPP1R18 PRPF18 PSMA1 RASAL3 RCOR3 RSPH14 RTL8A RTL8B RTL8C SDCBP SFN SGF29 SH3RF2 SLIRP SMARCD1 SNAPIN SORBS3 SPATA18 SPATA2 SPG21 SYCE1 SYT17 TCEANC TCP10L TFIP11 TNNI1 TPM3 TRIM27 TRIM54 TSGA10IP TTC23 VPS52 ZBTB32 ZBTB42 ZC2HC1C ZNF20 ZNF250 ZNF572 ZNF620 ZNF688 ZNF774	8 interacting genes: CCDC102B CDC23 CSNK2B GADD45A GSK3B LRR1 PFKFB1 PJA1
Entrez ID		79839	5210
HPRD ID		08038	05613
Ensembl ID		ENSG00000150636	ENSG00000114268
Uniprot IDs		Q68D86	B7Z5C3 Q16877 Q5XLC3 Q66S35
PDB IDs
Enriched GO Terms of Interacting Partners?
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