CCDC102B and TPM3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		CCDC102B	TPM3
Description		coiled-coil domain containing 102B	tropomyosin 3
Image		No pdb structure
GO Annotations	Cellular Component		Stress Fiber Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Actin Filament Actin Cytoskeleton Extracellular Exosome
	Molecular Function	Protein Binding	Molecular_function Protein Binding Actin Filament Binding
	Biological Process		Muscle Contraction Actin Filament Organization
Pathways			Striated Muscle Contraction Smooth Muscle Contraction RHOV GTPase cycle Signaling by ALK fusions and activated point mutants
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS		Caudate activity during reward ( 28927378) Liver enzyme levels (alanine transaminase) ( 24124411) Myopic maculopathy ( 29725004) Pursuit maintenance gain ( 29064472) Pursuit maintenance gain in psychotic disorders ( 29064472) Rostral anterior cingulate cortex volume ( 31530798)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010 32888494) Mean reticulocyte volume ( 32888494) Platelet count ( 27863252) Smoking initiation (ever regular vs never regular) ( 30679032) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		102 interacting genes: ABI2 AK8 ANKRD23 ARL4A ARL4D BYSL C20orf202 CACNB4 CAPN3 CCDC120 CCDC187 CCDC33 CCHCR1 CDK18 CEP19 CEP57L1 CWF19L2 DISC1 DOCK10 EFHC2 EHHADH ENKD1 EXOC5 FAM161A FAM217B FBF1 FH FLOT1 FNDC11 GEM GOPC HMG20B IKZF3 KIFC3 KPNA3 KRT75 KRTAP13-3 LENG1 LMO4 LNX1 LZTS1 MAB21L2 MAGOHB MARK1 MCM7 MEOX1 MEOX2 MFAP1 MOS MSX2 NIF3L1 NME4 NTAQ1 NXT2 PFKFB4 PHAF1 PICK1 PNMA5 POMC POP5 PPP1R13B PPP1R18 PRPF18 PSMA1 RASAL3 RCOR3 RSPH14 RTL8A RTL8B RTL8C SDCBP SFN SGF29 SH3RF2 SLIRP SMARCD1 SNAPIN SORBS3 SPATA18 SPATA2 SPG21 SYCE1 SYT17 TCEANC TCP10L TFIP11 TNNI1 TPM3 TRIM27 TRIM54 TSGA10IP TTC23 VPS52 ZBTB32 ZBTB42 ZC2HC1C ZNF20 ZNF250 ZNF572 ZNF620 ZNF688 ZNF774	59 interacting genes: ACTA1 ACTB BLOC1S6 C1orf216 CAVIN3 CCDC102B CCDC146 CCHCR1 CHRM3 CNN1 DVL2 FAM9C FBXO5 FGA HDDC3 HOOK2 HSF2 HSF4 IFIT3 IKBIP KCNE1 KIFC3 KXD1 LCA5L LURAP1 MAD1L1 MAGEA11 MAST2 NEK2 NOD2 NUP54 ODAD1 OIP5 PBX3 PHLDB3 PSMC5 S100A2 S100A4 SMAD3 SNAPIN SUMO4 SYCE1 TAB2 TFPT THAP1 THAP7 TLK1 TMOD1 TMOD2 TNNI1 TNNT1 TPM4 TRAP1 TRIM27 TRIP6 TSKS VPS52 WASH3P WASHC1
Entrez ID		79839	7170
HPRD ID		08038	01840
Ensembl ID		ENSG00000150636	ENSG00000143549
Uniprot IDs		Q68D86	A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4I4 B4DQ80 P06753
PDB IDs			6OTN
Enriched GO Terms of Interacting Partners?
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