PFKFB4 and CCDC102B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PFKFB4	CCDC102B
Description		6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	coiled-coil domain containing 102B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol
	Molecular Function	6-phosphofructo-2-kinase Activity Fructose-2,6-bisphosphate 2-phosphatase Activity Protein Binding ATP Binding	Protein Binding
	Biological Process	Fructose Metabolic Process Fructose 2,6-bisphosphate Metabolic Process Dephosphorylation Carbohydrate Phosphorylation
Pathways		Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
Drugs		Phosphoaminophosphonic Acid-Adenylate Ester Fructose-6-phosphate
Diseases
GWAS		Bitter beverage consumption ( 31046077) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Mental health study participation (completed survey) ( 31263887) Morning person ( 30696823) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908 25082827) Waist-hip index ( 34021172)	Caudate activity during reward ( 28927378) Liver enzyme levels (alanine transaminase) ( 24124411) Myopic maculopathy ( 29725004) Pursuit maintenance gain ( 29064472) Pursuit maintenance gain in psychotic disorders ( 29064472) Rostral anterior cingulate cortex volume ( 31530798)
Interacting Genes		8 interacting genes: CCDC102B CDC23 CSNK2B GADD45A GSK3B LRR1 PFKFB1 PJA1	102 interacting genes: ABI2 AK8 ANKRD23 ARL4A ARL4D BYSL C20orf202 CACNB4 CAPN3 CCDC120 CCDC187 CCDC33 CCHCR1 CDK18 CEP19 CEP57L1 CWF19L2 DISC1 DOCK10 EFHC2 EHHADH ENKD1 EXOC5 FAM161A FAM217B FBF1 FH FLOT1 FNDC11 GEM GOPC HMG20B IKZF3 KIFC3 KPNA3 KRT75 KRTAP13-3 LENG1 LMO4 LNX1 LZTS1 MAB21L2 MAGOHB MARK1 MCM7 MEOX1 MEOX2 MFAP1 MOS MSX2 NIF3L1 NME4 NTAQ1 NXT2 PFKFB4 PHAF1 PICK1 PNMA5 POMC POP5 PPP1R13B PPP1R18 PRPF18 PSMA1 RASAL3 RCOR3 RSPH14 RTL8A RTL8B RTL8C SDCBP SFN SGF29 SH3RF2 SLIRP SMARCD1 SNAPIN SORBS3 SPATA18 SPATA2 SPG21 SYCE1 SYT17 TCEANC TCP10L TFIP11 TNNI1 TPM3 TRIM27 TRIM54 TSGA10IP TTC23 VPS52 ZBTB32 ZBTB42 ZC2HC1C ZNF20 ZNF250 ZNF572 ZNF620 ZNF688 ZNF774
Entrez ID		5210	79839
HPRD ID		05613	08038
Ensembl ID		ENSG00000114268	ENSG00000150636
Uniprot IDs		B7Z5C3 Q16877 Q5XLC3 Q66S35	Q68D86
PDB IDs
Enriched GO Terms of Interacting Partners?
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