PALB2 and LRATD2

Number of citations of the paper that reports this interaction (PubMedID 25640309)
8

Data Source:
BioGRID (two hybrid)

		PALB2	LRATD2
Description		partner and localizer of BRCA2	LRAT domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Protein-containing Complex	Cytoplasm Plasma Membrane
	Molecular Function	DNA Binding Protein Binding	Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Somitogenesis Inner Cell Mass Cell Proliferation Mesoderm Development Animal Organ Morphogenesis Multicellular Organism Growth Post-anal Tail Morphogenesis Negative Regulation Of Apoptotic Process Embryonic Organ Development
Pathways		HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function
Drugs
Diseases
GWAS		Bipolar disorder ( 17554300)
Interacting Genes		32 interacting genes: BCAS3 BRCA2 CASZ1 CCL5 CST6 DIRAS3 ERRFI1 GREB1 H2BC3 H3C1 H4C1 HNRNPC IL13RA2 IL24 KEAP1 KLK6 LRATD2 LYPD3 MRC2 NAT2 PDS5B PRDM14 RAD51 RAD51AP1 RAD51C RHOBTB2 RNF168 SERPINB5 SNAI1 THRSP USP2 XRCC3	14 interacting genes: ADRB2 AP1M1 BAG4 CTNNA1 DDIT4L ESR2 FGFR4 NOTCH2 PALB2 PTPN1 SMAD4 TAX1BP1 UROD XRCC3
Entrez ID		79728	157638
HPRD ID		07966	11403
Ensembl ID		ENSG00000083093	ENSG00000168672
Uniprot IDs		H3BN63 Q86YC2	Q96KN1
PDB IDs		2W18 3EU7
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?