TBXA2R and RPGRIP1L

Number of citations of the paper that reports this interaction (PubMedID 19464661)
4

Data Source:
BioGRID (two hybrid, affinity chromatography technology, pull down)

		TBXA2R	RPGRIP1L
Description		thromboxane A2 receptor	RPGRIP1 like
Image
GO Annotations	Cellular Component	Acrosomal Vesicle Plasma Membrane Integral Component Of Plasma Membrane Nuclear Speck	Nucleoplasm Cytoplasm Centrosome Cytosol Axonemal Microtubule Plasma Membrane Cell-cell Junction Bicellular Tight Junction Cilium Axoneme Photoreceptor Connecting Cilium Ciliary Rootlet Ciliary Transition Zone Ciliary Basal Body
	Molecular Function	Thromboxane A2 Receptor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding Thromboxane A2 Receptor Binding
	Biological Process	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Nutrient Response To Xenobiotic Stimulus Second-messenger-mediated Signaling Positive Regulation Of Blood Coagulation Response To Testosterone Thromboxane A2 Signaling Pathway Response To Ethanol Positive Regulation Of Angiogenesis Positive Regulation Of Blood Pressure Positive Regulation Of Vasoconstriction Positive Regulation Of Smooth Muscle Contraction Regulation Of Catalytic Activity Cellular Response To Lipopolysaccharide Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis	In Utero Embryonic Development Establishment Of Planar Polarity Kidney Development Liver Development Establishment Or Maintenance Of Cell Polarity Determination Of Left/right Symmetry Regulation Of Smoothened Signaling Pathway Neural Tube Patterning Cerebellum Development Lateral Ventricle Development Olfactory Bulb Development Corpus Callosum Development Embryonic Forelimb Morphogenesis Embryonic Hindlimb Morphogenesis Nose Development Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Retinal Rod Cell Development Pericardium Development Cochlea Development Non-motile Cilium Assembly
Pathways		Prostanoid ligand receptors G alpha (q) signalling events G alpha (12/13) signalling events Thromboxane signalling through TP receptor	Hedgehog 'off' state Anchoring of the basal body to the plasma membrane
Drugs		Ridogrel Seratrodast Morniflumate
Diseases
GWAS			Abdominal subcutaneous adipose tissue volume ( 34128465) Bipolar disorder ( 21254220) Bipolar disorder or body mass index ( 31754094) Body mass index ( 29273807) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Eyebrow thickness ( 26926045) Facial morphology ( 31763980) Kidney volume ( 34128465) Plasma anti-thyroglobulin levels ( 29678681) Serum alkaline phosphatase levels ( 33547301) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Visceral adipose tissue volume ( 34128465) Weight ( 28552196)
Interacting Genes		35 interacting genes: ADIPOR1 ARL6IP6 C5orf46 EMP1 GJB2 GNA11 GNA12 GNA13 GNAI2 GNAQ GNAS GNB1 GNG2 GPRASP1 GRK5 GRK6 MFSD5 MS4A13 NME2 NOX1 PRDX4 PRKCA PSMA7 PSME3 PTGIR RAB11A RACK1 RAF1 RPGRIP1L SLC35B4 SLC41A1 TM4SF4 VRK2 YWHAZ ZDHHC15	3 interacting genes: CES1P1 SLC6A2 TBXA2R
Entrez ID		6915	23322
HPRD ID		01768	17204
Ensembl ID		ENSG00000006638	ENSG00000103494
Uniprot IDs		P21731 Q05C92 Q0VAB0	A0A087WX34 B7ZKJ9 H3BPS4 H3BV03 I3L1B5 Q68CZ1
PDB IDs		1LBN	2YRB
Enriched GO Terms of Interacting Partners?
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