TBXA2R and MFSD5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TBXA2R	MFSD5
Description		thromboxane A2 receptor	major facilitator superfamily domain containing 5
Image			No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Plasma Membrane Integral Component Of Plasma Membrane Nuclear Speck	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Thromboxane A2 Receptor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding Molybdate Ion Transmembrane Transporter Activity
	Biological Process	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Nutrient Response To Xenobiotic Stimulus Second-messenger-mediated Signaling Positive Regulation Of Blood Coagulation Response To Testosterone Thromboxane A2 Signaling Pathway Response To Ethanol Positive Regulation Of Angiogenesis Positive Regulation Of Blood Pressure Positive Regulation Of Vasoconstriction Positive Regulation Of Smooth Muscle Contraction Regulation Of Catalytic Activity Cellular Response To Lipopolysaccharide Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis	Molybdate Ion Transport
Pathways		Prostanoid ligand receptors G alpha (q) signalling events G alpha (12/13) signalling events Thromboxane signalling through TP receptor
Drugs		Ridogrel Seratrodast Morniflumate
Diseases
GWAS
Interacting Genes		35 interacting genes: ADIPOR1 ARL6IP6 C5orf46 EMP1 GJB2 GNA11 GNA12 GNA13 GNAI2 GNAQ GNAS GNB1 GNG2 GPRASP1 GRK5 GRK6 MFSD5 MS4A13 NME2 NOX1 PRDX4 PRKCA PSMA7 PSME3 PTGIR RAB11A RACK1 RAF1 RPGRIP1L SLC35B4 SLC41A1 TM4SF4 VRK2 YWHAZ ZDHHC15	61 interacting genes: ADGRE2 AQP6 ARL6IP1 BEST2 BLCAP BTNL9 C2CD2L CBARP CCL4L2 CD40 CD79A CLDN7 CLRN1 CREB3 CREB3L1 CYB5B ERRFI1 FFAR2 FXYD3 GJA5 GLP1R GOSR2 GPR101 GPR152 GPR25 GPR42 GPX8 HSD17B13 IGFBP5 IL27RA KASH5 LAT LHFPL5 LMNA MMGT1 MUC1 PEX19 PGRMC2 PKMYT1 PLN RNF144A RNF19B RTP2 SCN3B SEC22B SHISAL1 SLC10A6 SLC18A2 SLC39A9 SSMEM1 STATH TBXA2R TIMMDC1 TMEM128 TMEM130 TMEM14B TMEM179B TMEM203 TMEM237 XRN1 YIPF6
Entrez ID		6915	84975
HPRD ID		01768	14416
Ensembl ID		ENSG00000006638	ENSG00000182544
Uniprot IDs		P21731 Q05C92 Q0VAB0	Q6N075
PDB IDs		1LBN
Enriched GO Terms of Interacting Partners?
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