Description |
mitogen-activated protein kinase kinase 6 |
fibroblast growth factor receptor 4 |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Body shape index ( 34021172)
- Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872)
- Eye color ( 33692100)
- Optic disc size ( 31809533)
- Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy) ( 24554482)
- Response to TNF-alpha inhibitors in rheumatoid arthritis ( 22569225)
- Waist-hip ratio ( 28552196)
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- Activated partial thromboplastin time ( 22703881)
- Apolipoprotein A1 levels ( 32203549)
- Body fat distribution (arm fat ratio) ( 30664634)
- Body fat distribution (trunk fat ratio) ( 30664634)
- Body shape index ( 34021172)
- Circulating fibroblast growth factor 23 levels ( 30217807)
- Height ( 28552196 25282103 31562340)
- Hemoglobin levels ( 32327693)
- Hip circumference adjusted for BMI ( 34021172)
- Hip index ( 34021172)
- Hip shape (DXA scan) ( 30320955)
- Narrowest width of the femoral neck ( 30888730)
- Nonsyndromic cleft lip ( 31609978)
- Type 2 diabetes ( 32499647 30718926)
- Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
- Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist circumference adjusted for BMI in active individuals ( 28448500)
- Waist circumference adjusted for BMI in non-smokers ( 28443625)
- Waist circumference adjusted for BMI in smokers ( 28443625)
- Waist circumference adjusted for body mass index ( 34021172 25673412 28448500)
- Waist-hip index ( 34021172)
- Waist-to-hip ratio adjusted for BMI ( 34021172 26426971)
- Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
- Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
- Waist-to-hip ratio adjusted for body mass index ( 26785701 25673412)
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Interacting Genes |
39 interacting genes:
AKT1
BECN1
BRAF
CCND2
CDKN2B
DCTN1
EPHA2
FBXO7
FGFR4
GLIS2
HGF
HRAS
LRRK2
MAP2K3
MAP2K4
MAP2K5
MAP3K20
MAP3K4
MAP3K5
MAP3K7
MAPK1
MAPK12
MAPK13
MAPK14
MAPKAPK2
MLH1
NFE2L2
PICK1
PKN1
PLCB2
RAF1
RASSF1
RELA
SMAD7
STAT4
STK11
TAOK2
TLR3
TRAF6
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85 interacting genes:
ABCB5
AKT1
ANGPTL4
ARAF
ARNT
BECN1
BLID
CASC3
CBLC
CCND2
CCNE1
CD44
CDH2
CDK4
CDK6
CDKN2A
CDKN2B
CDKN2C
DIRAS3
EPHA2
EPHA4
EPSTI1
ERBB2
ERRFI1
FGF1
FGF17
FGF18
FGF19
FGF2
FGF3
FGF4
FGF5
FGF6
FGF7
FGF8
FGF9
FZR1
GLCE
GLIS2
GRM1
HGF
HIF1A
IFT80
IGF1R
KDELR2
LATS2
LRATD2
MAP2K5
MAP2K6
MAP3K5
MAPK14
MDM4
MET
MSH2
MTA3
MYC
NF2
NSD3
OSGIN1
PDGFRA
PDLIM2
PLCG1
PPP3CA
PSMC3IP
PTPN11
PTPN12
PTPN6
PTPRR
RAF1
RASL10B
RASSF1
RNF20
ROS1
SCGB3A1
STAT1
STAT3
STC2
STK11
TEAD2
TERT
THRSP
TP53
TSC1
TTYH2
WIF1
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Entrez ID |
5608 |
2264 |
HPRD ID |
03155 |
00625 |
Ensembl ID |
ENSG00000108984
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ENSG00000160867
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Uniprot IDs |
A0A024R8K3
A8K3Y2
P52564
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B4DVP5
J3KPQ0
P22455
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PDB IDs |
2Y8O
3ENM
3FME
3VN9
5ETF
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1QCT
4QQ5
4QQC
4QQJ
4QQT
4QRC
4R6V
4TYE
4TYG
4TYI
4TYJ
4UXQ
4XCU
5JKG
5NUD
5NWZ
5XFF
5XFJ
6IUO
6IUP
6J6Y
6JPE
6JPJ
6NVG
6NVH
6NVI
6NVJ
6NVK
6V9C
6YI8
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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