Description |
mitogen-activated protein kinase kinase 6 |
mitogen-activated protein kinase kinase kinase 4 |
Image |
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No pdb structure |
GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Body shape index ( 34021172)
- Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872)
- Eye color ( 33692100)
- Optic disc size ( 31809533)
- Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy) ( 24554482)
- Response to TNF-alpha inhibitors in rheumatoid arthritis ( 22569225)
- Waist-hip ratio ( 28552196)
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- Aging ( 22773346)
- Blood protein levels ( 28240269)
- Cognitive decline rate in late mild cognitive impairment ( 26252872)
- Lipoprotein (a) levels ( 26377243)
- Ovarian disease with few adhesions ( 28333195)
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Interacting Genes |
39 interacting genes:
AKT1
BECN1
BRAF
CCND2
CDKN2B
DCTN1
EPHA2
FBXO7
FGFR4
GLIS2
HGF
HRAS
LRRK2
MAP2K3
MAP2K4
MAP2K5
MAP3K20
MAP3K4
MAP3K5
MAP3K7
MAPK1
MAPK12
MAPK13
MAPK14
MAPKAPK2
MLH1
NFE2L2
PICK1
PKN1
PLCB2
RAF1
RASSF1
RELA
SMAD7
STAT4
STK11
TAOK2
TLR3
TRAF6
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27 interacting genes:
ANXA2
AXIN1
BUB1B
CDC42
CHUK
CNTRL
DIXDC1
EPHB4
GADD45A
GADD45B
GADD45G
GSK3B
MAP2K1
MAP2K3
MAP2K4
MAP2K6
MAP2K7
MAPK13
MFHAS1
PTK2B
PTPN11
RAC1
RACGAP1
RUNX2
TPR
TRAF4
YWHAZ
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Entrez ID |
5608 |
4216 |
HPRD ID |
03155 |
03886 |
Ensembl ID |
ENSG00000108984
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ENSG00000085511
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Uniprot IDs |
A0A024R8K3
A8K3Y2
P52564
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Q9P1M2
Q9Y6R4
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PDB IDs |
2Y8O
3ENM
3FME
3VN9
5ETF
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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