PPP2R3C and CCDC146

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PPP2R3C	CCDC146
Description		protein phosphatase 2 regulatory subunit B''gamma	coiled-coil domain containing 146
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Golgi Apparatus Centrosome Spindle Cytosol	Cytoplasm Centriole Cytoskeleton
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization B Cell Homeostasis Regulation Of Antimicrobial Humoral Response Cortical Cytoskeleton Organization Activation Of Protein Kinase Activity Regulation Of Dephosphorylation T Cell Homeostasis Positive Regulation Of B Cell Differentiation Spleen Development Regulation Of Mitochondrial Depolarization
Pathways
Drugs
Diseases
GWAS		Atopic dermatitis ( 26482879) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Colorectal carcinoma in primary sclerosing cholangitis ( 28779025) Lymphocyte counts ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494)	Body mass index ( 28892062) Macrovascular complications in type 2 diabetes ( 33430853) Ophthalmic complications in type 2 diabetes ( 33430853) Response to amphetamines ( 22952603)
Interacting Genes		15 interacting genes: CCDC146 CCDC33 CMTM5 ENKD1 FAM161A FAM161B HSPB1 IKBKB MOAP1 MTNR1A POLR1C PRPF31 RTN3 SMG9 TRIM14	71 interacting genes: AKAP9 BLOC1S2 CBY2 CCDC136 CCDC197 CCNDBP1 CDR2 CDR2L CENPH CEP170P1 CEP44 DTNBP1 FSD2 GAS8 GMNN GOLGA2 GOLGA6L9 GPRASP2 GRAMD4 HSF2BP INSYN1 KIFC3 KRT16 KRT18 KRT19 KRT24 KRT26 KRT27 KRT31 KRT34 KRT38 KRT40 KRT86 LHX3 MAGEA11 MAGEA6 MCC MED4 MIPOL1 MRFAP1 MTUS2 N4BP3 NAP1L2 NECAB2 NINL NUP62 PDE4DIP PLEKHF2 PNMA1 PPP2R3C PROSER3 PSMC6 RINT1 RNF40 RPGRIP1 SH3BP1 SYCE1L TEPSIN TFIP11 THOC7 TNR TPM3 TRAF1 TRIM23 TRIM54 TRIML2 TSC22D4 TXLNA USHBP1 VPS28 VPS52
Entrez ID		55012	57639
HPRD ID		12622	11150
Ensembl ID		ENSG00000092020	ENSG00000135205
Uniprot IDs		Q969Q6	Q8IYE0 Q96MS1
PDB IDs
Enriched GO Terms of Interacting Partners?
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