CCDC146 and GRAMD4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CCDC146	GRAMD4
Description		coiled-coil domain containing 146	GRAM domain containing 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centriole Cytoskeleton	Mitochondrion Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding	Molecular_function Protein Binding
	Biological Process		Apoptotic Process Negative Regulation Of Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Body mass index ( 28892062) Macrovascular complications in type 2 diabetes ( 33430853) Ophthalmic complications in type 2 diabetes ( 33430853) Response to amphetamines ( 22952603)	Urate levels in obese individuals ( 25811787)
Interacting Genes		71 interacting genes: AKAP9 BLOC1S2 CBY2 CCDC136 CCDC197 CCNDBP1 CDR2 CDR2L CENPH CEP170P1 CEP44 DTNBP1 FSD2 GAS8 GMNN GOLGA2 GOLGA6L9 GPRASP2 GRAMD4 HSF2BP INSYN1 KIFC3 KRT16 KRT18 KRT19 KRT24 KRT26 KRT27 KRT31 KRT34 KRT38 KRT40 KRT86 LHX3 MAGEA11 MAGEA6 MCC MED4 MIPOL1 MRFAP1 MTUS2 N4BP3 NAP1L2 NECAB2 NINL NUP62 PDE4DIP PLEKHF2 PNMA1 PPP2R3C PROSER3 PSMC6 RINT1 RNF40 RPGRIP1 SH3BP1 SYCE1L TEPSIN TFIP11 THOC7 TNR TPM3 TRAF1 TRIM23 TRIM54 TRIML2 TSC22D4 TXLNA USHBP1 VPS28 VPS52	14 interacting genes: APP C2CD6 CCDC146 EXOC8 FAM9B GADD45G MTMR9 NTAQ1 PKDREJ PLEKHF2 RBL2 SH2D4A SMARCD1 TACC2
Entrez ID		57639	23151
HPRD ID		11150	11107
Ensembl ID		ENSG00000135205	ENSG00000075240
Uniprot IDs		Q8IYE0 Q96MS1	Q6IC98
PDB IDs
Enriched GO Terms of Interacting Partners?
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