CCDC146 and TRIML2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CCDC146	TRIML2
Description		coiled-coil domain containing 146	tripartite motif family like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centriole Cytoskeleton	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding Protein Kinase Binding Identical Protein Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity
	Biological Process		Protein Polyubiquitination Regulation Of Gene Expression Positive Regulation Of Autophagy Protein Ubiquitination Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Regulation Of Viral Entry Into Host Cell Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways
Drugs
Diseases
GWAS		Body mass index ( 28892062) Macrovascular complications in type 2 diabetes ( 33430853) Ophthalmic complications in type 2 diabetes ( 33430853) Response to amphetamines ( 22952603)	Polycystic ovary syndrome ( 25574032)
Interacting Genes		71 interacting genes: AKAP9 BLOC1S2 CBY2 CCDC136 CCDC197 CCNDBP1 CDR2 CDR2L CENPH CEP170P1 CEP44 DTNBP1 FSD2 GAS8 GMNN GOLGA2 GOLGA6L9 GPRASP2 GRAMD4 HSF2BP INSYN1 KIFC3 KRT16 KRT18 KRT19 KRT24 KRT26 KRT27 KRT31 KRT34 KRT38 KRT40 KRT86 LHX3 MAGEA11 MAGEA6 MCC MED4 MIPOL1 MRFAP1 MTUS2 N4BP3 NAP1L2 NECAB2 NINL NUP62 PDE4DIP PLEKHF2 PNMA1 PPP2R3C PROSER3 PSMC6 RINT1 RNF40 RPGRIP1 SH3BP1 SYCE1L TEPSIN TFIP11 THOC7 TNR TPM3 TRAF1 TRIM23 TRIM54 TRIML2 TSC22D4 TXLNA USHBP1 VPS28 VPS52	48 interacting genes: ABI2 BLOC1S2 CBY2 CCDC146 CCDC92 CCHCR1 CCNH CDR2 CTBP2 EIF2B1 EIF3M FAM90A1 FAM9C HGS ING5 ITGB3BP KRT15 KRT24 KRT27 KRT31 KRT34 KRT38 KRT75 MBD3L2 MBD3L3 MEOX1 MEOX2 NECAB2 NFKBID NUP62 PICK1 POLR1H POU6F2 SH2D4A STN1 SUMO2 SYCE2 TBC1D25 TCF4 TFIP11 TRIM54 TSEN54 TSG101 USHBP1 XAF1 ZBED1 ZBTB33 ZFHX3
Entrez ID		57639	205860
HPRD ID		11150	08696
Ensembl ID		ENSG00000135205	ENSG00000179046
Uniprot IDs		Q8IYE0 Q96MS1	B7ZLC3 Q8N7C3
PDB IDs
Enriched GO Terms of Interacting Partners?
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