PFDN1 and ESS2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

		PFDN1	ESS2
Description		prefoldin subunit 1	ess-2 splicing factor homolog
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Prefoldin Complex	Nucleus Catalytic Step 2 Spliceosome
	Molecular Function	Amyloid-beta Binding Protein Binding Protein Folding Chaperone Unfolded Protein Binding	Molecular_function Protein Binding
	Biological Process	Protein Folding Negative Regulation Of Amyloid Fibril Formation	MRNA Splicing, Via Spliceosome Nervous System Development
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS		Alzheimer's disease ( 28183528) Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Reaction time ( 29844566)
Interacting Genes		54 interacting genes: ACTA1 ACTB ALB BRK1 CCDC85A CEP126 CHGA DCTN1 DEFA1 DMAP1 EDRF1 EIF3C EIF4A2 EOMES ESS2 EXT2 EZH2 FAM20C GET3 GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 YEATS4 ZNF235	19 interacting genes: ARMC7 CCDC57 CDK5RAP3 CRP DGCR6 DHX16 EXOC8 FRA10AC1 LYST OGT OIP5 PFDN1 QARS1 RACK1 RBM4 SMARCD1 TTC14 VIM WNK2
Entrez ID		5201	8220
HPRD ID		05357	03452
Ensembl ID		ENSG00000113068	ENSG00000100056
Uniprot IDs		O60925	F8WEF8 Q96DF8
PDB IDs		6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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