PFDN1 and IMMT

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		PFDN1	IMMT
Description		prefoldin subunit 1	inner membrane mitochondrial protein
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Prefoldin Complex	SAM Complex Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Membrane MICOS Complex MIB Complex
	Molecular Function	Amyloid-beta Binding Protein Binding Protein Folding Chaperone Unfolded Protein Binding	RNA Binding Protein Binding
	Biological Process	Protein Folding Negative Regulation Of Amyloid Fibril Formation	Inner Mitochondrial Membrane Organization Cristae Formation Mitochondrial Calcium Ion Homeostasis
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC	Cristae formation
Drugs
Diseases
GWAS		Alzheimer's disease ( 28183528) Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Reaction time ( 29844566)	Facial emotion recognition (sad faces) ( 28608620) Night sleep phenotypes ( 27126917)
Interacting Genes		54 interacting genes: ACTA1 ACTB ALB BRK1 CCDC85A CEP126 CHGA DCTN1 DEFA1 DMAP1 EDRF1 EIF3C EIF4A2 EOMES ESS2 EXT2 EZH2 FAM20C GET3 GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 YEATS4 ZNF235	59 interacting genes: AKTIP ALB ANTKMT ARMCX3 ASCC2 ATXN1 BAG6 BMI1 C10orf88 C8orf33 CALM1 CCDC113 CCT5 CDC37 CHD3 CSTF2 DISC1 ECSIT EEF1A1 EP300 EXOSC10 FEZ1 FUBP1 HAP1 HIVEP1 HJURP HMOX2 HNRNPD HTRA2 KDM1A KIF22 KPNA2 LRIF1 MRPL44 MRPS5 NDEL1 NDUFB9 NEK2 NIPSNAP3A NOS3 PFDN1 PIAS4 PLA2G15 PPOX PRRC2A RER1 SDHAF2 SMN1 SNAPIN SRRT STMN4 STX5 TAF1D TK1 TNNT1 TRAF3IP1 TUBGCP3 TXNDC9 UBQLN4
Entrez ID		5201	10989
HPRD ID		05357	02658
Ensembl ID		ENSG00000113068	ENSG00000132305
Uniprot IDs		O60925	Q16891
PDB IDs		6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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