PFDN1 and PFDN2

Number of citations of the paper that reports this interaction (PubMedID 14634002)
18

Data Source:
HPRD (in vitro)

		PFDN1	PFDN2
Description		prefoldin subunit 1	prefoldin subunit 2
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GO Annotations	Cellular Component	Cytoplasm Prefoldin Complex	Nucleus Cytoplasm Mitochondrion Cytosol Prefoldin Complex
	Molecular Function	Amyloid-beta Binding Protein Binding Protein Folding Chaperone Unfolded Protein Binding	Amyloid-beta Binding Protein Binding Protein Folding Chaperone Unfolded Protein Binding
	Biological Process	Protein Folding Negative Regulation Of Amyloid Fibril Formation	Protein Folding Positive Regulation Of Cytoskeleton Organization Negative Regulation Of Amyloid Fibril Formation
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC	Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS		Alzheimer's disease ( 28183528) Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Reaction time ( 29844566)
Interacting Genes		54 interacting genes: ACTA1 ACTB ALB BRK1 CCDC85A CEP126 CHGA DCTN1 DEFA1 DMAP1 EDRF1 EIF3C EIF4A2 EOMES ESS2 EXT2 EZH2 FAM20C GET3 GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 YEATS4 ZNF235	9 interacting genes: DBI ERBB3 MAP3K3 PFDN1 PFDN4 RGS4 SNCA VBP1 ZNF726
Entrez ID		5201	5202
HPRD ID		05357	09658
Ensembl ID		ENSG00000113068	ENSG00000143256
Uniprot IDs		O60925	B1AQP2 Q9UHV9
PDB IDs		6NR8 6NR9 6NRB 6NRC 6NRD	6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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