ASS1 and ASCC2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ASS1	ASCC2
Description		argininosuccinate synthase 1	activating signal cointegrator 1 complex subunit 2
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrial Outer Membrane Lysosome Endoplasmic Reticulum Cytosol Perikaryon Extracellular Exosome Cell Body Fiber	Nucleus Nucleoplasm Nuclear Speck Activating Signal Cointegrator 1 Complex
	Molecular Function	RNA Binding Argininosuccinate Synthase Activity Protein Binding ATP Binding Toxic Substance Binding Amino Acid Binding Identical Protein Binding	Protein Binding Ubiquitin Binding
	Biological Process	Urea Cycle Citrulline Metabolic Process Argininosuccinate Metabolic Process Kidney Development Liver Development Arginine Biosynthetic Process Aspartate Metabolic Process Acute-phase Response Midgut Development Aging Response To Nutrient Circadian Rhythm Response To Xenobiotic Stimulus Response To Zinc Ion Response To Mycotoxin Response To Estradiol Positive Regulation Of Nitric Oxide Biosynthetic Process Response To Growth Hormone Diaphragm Development Cellular Response To Lipopolysaccharide Cellular Response To Amino Acid Stimulus Cellular Response To Ammonium Ion Cellular Response To CAMP Cellular Response To Interferon-gamma Cellular Response To Tumor Necrosis Factor Cellular Response To Glucagon Stimulus Cellular Response To Oleic Acid Cellular Response To Amine Stimulus Cellular Response To Laminar Fluid Shear Stress Cellular Response To Dexamethasone Stimulus Negative Regulation Of Leukocyte Cell-cell Adhesion	DNA Repair Regulation Of Transcription, DNA-templated Rescue Of Stalled Ribosome Ribosome-associated Ubiquitin-dependent Protein Catabolic Process
Pathways		Urea cycle	ALKBH3 mediated reversal of alkylation damage
Drugs		Arginine Aspartic acid Aspartic acid Citrulline Citrulline ATP
Diseases
GWAS			Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Crohn's disease ( 28067908) Hemoglobin levels ( 32327693) IgA levels ( 28628107) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin concentration ( 32888494) Refractive error ( 32231278) Spleen volume ( 34128465) Telomere length ( 24478790) Tonsillectomy ( 27941131) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		18 interacting genes: AKTIP APP ARAF ASCC2 ELN JAK2 LINC01554 MLH1 MT2A NUP214 PMPCA PTPN1 SLC13A1 STOM SUMO2 TERF1 TERF2 USP4	41 interacting genes: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT KATNAL1 KDM1A LPL MAP3K1 MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 PRPF18 RADIL RNF11 RPA1 RPLP1 SASH1 SMURF1 SNRPB SNW1 TBC1D17 TRIP4 UBC URM1
Entrez ID		445	84164
HPRD ID		04590	16515
Ensembl ID		ENSG00000130707	ENSG00000100325
Uniprot IDs		P00966 Q5T6L4	A0A024R1E1 A0A024R1F9 Q9H1I8
PDB IDs		2NZ2	2DI0 6YXQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?