ASCC2 and ELAC2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ASCC2	ELAC2
Description		activating signal cointegrator 1 complex subunit 2	elaC ribonuclease Z 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck Activating Signal Cointegrator 1 Complex	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol Mitochondrial Nucleoid
	Molecular Function	Protein Binding Ubiquitin Binding	RNA Binding Endoribonuclease Activity TRNA-specific Ribonuclease Activity 3'-tRNA Processing Endoribonuclease Activity Metal Ion Binding
	Biological Process	DNA Repair Regulation Of Transcription, DNA-templated Rescue Of Stalled Ribosome Ribosome-associated Ubiquitin-dependent Protein Catabolic Process	TRNA Catabolic Process TRNA 3'-end Processing Mitochondrial TRNA 3'-trailer Cleavage, Endonucleolytic Mitochondrial TRNA Processing
Pathways		ALKBH3 mediated reversal of alkylation damage	tRNA processing in the nucleus tRNA processing in the mitochondrion rRNA processing in the mitochondrion tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis
Drugs
Diseases
GWAS		Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Crohn's disease ( 28067908) Hemoglobin levels ( 32327693) IgA levels ( 28628107) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin concentration ( 32888494) Refractive error ( 32231278) Spleen volume ( 34128465) Telomere length ( 24478790) Tonsillectomy ( 27941131) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382)	Squamous cell lung carcinoma ( 28604730)
Interacting Genes		41 interacting genes: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT KATNAL1 KDM1A LPL MAP3K1 MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 PRPF18 RADIL RNF11 RPA1 RPLP1 SASH1 SMURF1 SNRPB SNW1 TBC1D17 TRIP4 UBC URM1	11 interacting genes: ASCC2 CTBP1 CTBP2 CUX1 DRC3 GID4 GOLM1 NDUFA7 RING1 SMAD2 SUMO2
Entrez ID		84164	60528
HPRD ID		16515	05641
Ensembl ID		ENSG00000100325	ENSG00000006744
Uniprot IDs		A0A024R1E1 A0A024R1F9 Q9H1I8	A0A0S2Z5M8 Q9BQ52
PDB IDs		2DI0 6YXQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?