ASCC2 and PIN4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ASCC2	PIN4
Description		activating signal cointegrator 1 complex subunit 2	peptidylprolyl cis/trans isomerase, NIMA-interacting 4
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck Activating Signal Cointegrator 1 Complex	Nucleoplasm Chromosome Nucleolus Mitochondrial Matrix Spindle
	Molecular Function	Protein Binding Ubiquitin Binding	DNA Binding RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding
	Biological Process	DNA Repair Regulation Of Transcription, DNA-templated Rescue Of Stalled Ribosome Ribosome-associated Ubiquitin-dependent Protein Catabolic Process	Protein Peptidyl-prolyl Isomerization RRNA Processing
Pathways		ALKBH3 mediated reversal of alkylation damage
Drugs
Diseases
GWAS		Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Crohn's disease ( 28067908) Hemoglobin levels ( 32327693) IgA levels ( 28628107) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin concentration ( 32888494) Refractive error ( 32231278) Spleen volume ( 34128465) Telomere length ( 24478790) Tonsillectomy ( 27941131) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382)	Rosacea symptom severity ( 29771307)
Interacting Genes		41 interacting genes: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT KATNAL1 KDM1A LPL MAP3K1 MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 PRPF18 RADIL RNF11 RPA1 RPLP1 SASH1 SMURF1 SNRPB SNW1 TBC1D17 TRIP4 UBC URM1	19 interacting genes: ASCC2 CEP72 CSNK2A1 CSNK2A2 DNM1 EGFR ERBB2 ERBB3 ERBB4 EZH2 FAM9B FATE1 FBL FRMD1 MAD1L1 MAGEA11 PNMA1 SPTAN1 ZBTB9
Entrez ID		84164	5303
HPRD ID		16515	02219
Ensembl ID		ENSG00000100325	ENSG00000102309
Uniprot IDs		A0A024R1E1 A0A024R1F9 Q9H1I8	Q9Y237
PDB IDs		2DI0 6YXQ	1EQ3 1FJD 3UI4 3UI5 3UI6
Enriched GO Terms of Interacting Partners?
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