ASCC2 and POLDIP2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ASCC2	POLDIP2
Description		activating signal cointegrator 1 complex subunit 2	DNA polymerase delta interacting protein 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck Activating Signal Cointegrator 1 Complex	Nucleus Mitochondrion Mitochondrial Matrix Plasma Membrane Cell-cell Junction Midbody Mitochondrial Nucleoid Mitotic Spindle
	Molecular Function	Protein Binding Ubiquitin Binding	DNA Binding Protein Binding
	Biological Process	DNA Repair Regulation Of Transcription, DNA-templated Rescue Of Stalled Ribosome Ribosome-associated Ubiquitin-dependent Protein Catabolic Process	Negative Regulation Of Macroautophagy Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Focal Adhesion Assembly Mitochondrion Morphogenesis Error-free Translesion Synthesis Mitotic Spindle Assembly Positive Regulation Of Mitotic Cytokinesis Positive Regulation Of Actin Filament Binding Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity
Pathways		ALKBH3 mediated reversal of alkylation damage
Drugs
Diseases
GWAS		Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Crohn's disease ( 28067908) Hemoglobin levels ( 32327693) IgA levels ( 28628107) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin concentration ( 32888494) Refractive error ( 32231278) Spleen volume ( 34128465) Telomere length ( 24478790) Tonsillectomy ( 27941131) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382)	Blood protein levels ( 29875488) Osteoprotegerin levels ( 25080503)
Interacting Genes		41 interacting genes: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT KATNAL1 KDM1A LPL MAP3K1 MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 PRPF18 RADIL RNF11 RPA1 RPLP1 SASH1 SMURF1 SNRPB SNW1 TBC1D17 TRIP4 UBC URM1	20 interacting genes: AGTRAP ALAS1 APP ASCC2 CHCHD2 CPE DNAAF6 FBXO7 HDAC6 MAD2L2 MTUS2 PCNA PDPK1 POLD2 POLN PTEN REV1 SELENBP1 TAB1 TMEM97
Entrez ID		84164	26073
HPRD ID		16515	17874
Ensembl ID		ENSG00000100325	ENSG00000004142
Uniprot IDs		A0A024R1E1 A0A024R1F9 Q9H1I8	B4DEM9 Q9Y2S7
PDB IDs		2DI0 6YXQ	6Z9C
Enriched GO Terms of Interacting Partners?
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