ASS1 and SLC13A1

Number of citations of the paper that reports this interaction (PubMedID 18407958)
29

Data Source:
BioGRID (protein complementation assay)

		ASS1	SLC13A1
Description		argininosuccinate synthase 1	solute carrier family 13 member 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrial Outer Membrane Lysosome Endoplasmic Reticulum Cytosol Perikaryon Extracellular Exosome Cell Body Fiber	Plasma Membrane Integral Component Of Membrane
	Molecular Function	RNA Binding Argininosuccinate Synthase Activity Protein Binding ATP Binding Toxic Substance Binding Amino Acid Binding Identical Protein Binding	Sodium:sulfate Symporter Activity
	Biological Process	Urea Cycle Citrulline Metabolic Process Argininosuccinate Metabolic Process Kidney Development Liver Development Arginine Biosynthetic Process Aspartate Metabolic Process Acute-phase Response Midgut Development Aging Response To Nutrient Circadian Rhythm Response To Xenobiotic Stimulus Response To Zinc Ion Response To Mycotoxin Response To Estradiol Positive Regulation Of Nitric Oxide Biosynthetic Process Response To Growth Hormone Diaphragm Development Cellular Response To Lipopolysaccharide Cellular Response To Amino Acid Stimulus Cellular Response To Ammonium Ion Cellular Response To CAMP Cellular Response To Interferon-gamma Cellular Response To Tumor Necrosis Factor Cellular Response To Glucagon Stimulus Cellular Response To Oleic Acid Cellular Response To Amine Stimulus Cellular Response To Laminar Fluid Shear Stress Cellular Response To Dexamethasone Stimulus Negative Regulation Of Leukocyte Cell-cell Adhesion	Sodium Ion Transport Sulfate Transport Anion Transmembrane Transport Sulfate Transmembrane Transport
Pathways		Urea cycle	Sodium-coupled sulphate, di- and tri-carboxylate transporters
Drugs		Arginine Aspartic acid Aspartic acid Citrulline Citrulline ATP
Diseases
GWAS			Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel) ( 23648065) High density lipoprotein cholesterol levels ( 30498476) Systolic blood pressure ( 30578418)
Interacting Genes		18 interacting genes: AKTIP APP ARAF ASCC2 ELN JAK2 LINC01554 MLH1 MT2A NUP214 PMPCA PTPN1 SLC13A1 STOM SUMO2 TERF1 TERF2 USP4	31 interacting genes: ACOT2 ACTR10 APLP2 ARL6IP1 ASS1 CD59 COQ5 COQ9 CRYAB DYNLL1 FTL GRN HSPA1A MKRN1 NDUFS5 OGDHL PDZK1 PNPLA6 PRSS8 RHOA SDHD SEC61A1 SELPLG SERPINA1 SLC9A3R1 SLC9A3R2 TBRG1 TM4SF1 TMED10 TP53I11 TSPAN3
Entrez ID		445	6561
HPRD ID		04590	08394
Ensembl ID		ENSG00000130707	ENSG00000081800
Uniprot IDs		P00966 Q5T6L4	A4D0X1 Q2NKK0 Q9BZW2
PDB IDs		2NZ2
Enriched GO Terms of Interacting Partners?
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