KIR3DL1 and RPS6KB1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		KIR3DL1	RPS6KB1
Description		killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1	ribosomal protein S6 kinase B1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol Neuron Projection Synapse
	Molecular Function	Amyloid-beta Binding Protein Binding HLA-B Specific Inhibitory MHC Class I Receptor Activity	Protein Kinase Activity Protein Serine/threonine Kinase Activity Ribosomal Protein S6 Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Immune Response Natural Killer Cell Mediated Cytotoxicity	G1/S Transition Of Mitotic Cell Cycle Apoptotic Process Signal Transduction Peptidyl-serine Phosphorylation Response To Nutrient Levels TOR Signaling Cellular Response To Insulin Stimulus Negative Regulation Of Apoptotic Process Long-chain Fatty Acid Import Into Cell Positive Regulation Of Translation Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Translational Initiation Negative Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Cellular Response To Growth Factor Stimulus
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	mTORC1-mediated signalling
Drugs
Diseases
GWAS		Lymphocyte counts ( 32888494) Ulcerative colitis ( 28067908)	Body shape index ( 34021172) C-reactive protein levels ( 30388399) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Chronic lymphocytic leukemia or multiple sclerosis ( 31407831) Crohn's disease ( 28067908) Inflammatory bowel disease ( 23128233) Multiple sclerosis ( 21833088) Obesity-related traits ( 23251661) Triglycerides ( 30275531)
Interacting Genes		10 interacting genes: BMP10 CDK3 FPR1 HLA-B KIR2DS1 KIR2DS5 KIR3DS1 RPS6KB1 SMCO4 THSD7B	62 interacting genes: ACTA1 AKT1 APP BTK CDC42 CDK1 CLEC3B COASY CSNK2A1 CSNK2B CYB5R3 DEPTOR DPPA4 EEF2K EIF3B EIF3F EIF4B EIF4EBP1 EP300 FBXO7 GDI2P1 GRIA1 HTT IRS1 KAT2B KIR3DL1 LYN MAPK1 MAPK3 MAPK8 MAPK9 MAPT MARK2 MTOR MXD1 NCBP1 NEDD4 NEK6 NR1I2 PDK1 PDPK1 PIK3CA PIN1 PIP4K2A POLDIP3 PPP1R9A PPP1R9B PPP2CA RAC1 RBX1 RHEB RPS6 RPTOR SRC STK11 SYK TBK1 TERT TRAF4 URI1 USP11 XPO1
Entrez ID		3811	6198
HPRD ID		09226	10202
Ensembl ID		ENSG00000167633	ENSG00000108443
Uniprot IDs		P43629 Q5UCE2 Q6H2G3 Q8N6C9	P23443
PDB IDs		3VH8 3WUW 5B38 5B39 5T6Z 5T70 6V3J 7K80	3A60 3A61 3A62 3WE4 3WF5 3WF6 3WF7 3WF8 3WF9 4L3J 4L3L 4L42 4L43 4L44 4L45 4L46 4RLO 4RLP 5WBH 5WBK
Enriched GO Terms of Interacting Partners?
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