KIR3DL1 and SMCO4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KIR3DL1	SMCO4
Description		killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1	single-pass membrane protein with coiled-coil domains 4
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Cellular_component Integral Component Of Membrane
	Molecular Function	Amyloid-beta Binding Protein Binding HLA-B Specific Inhibitory MHC Class I Receptor Activity	Molecular_function Protein Binding
	Biological Process	Immune Response Natural Killer Cell Mediated Cytotoxicity	Biological_process
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Lymphocyte counts ( 32888494) Ulcerative colitis ( 28067908)	Adult body size ( 32376654) Insulin levels in response to oral glucose tolerance test (30 minutes) ( 29093273) Liver enzyme levels (alanine transaminase) ( 33972514)
Interacting Genes		10 interacting genes: BMP10 CDK3 FPR1 HLA-B KIR2DS1 KIR2DS5 KIR3DS1 RPS6KB1 SMCO4 THSD7B	60 interacting genes: AQP6 ATP2A2 BNIP3L CD79A CLEC10A CLTRN CPLX4 CREB3L1 CXCR2 EBP ERGIC3 FAM174A FAM209A FAM210B FFAR2 GJA8 GKN1 GPA33 GPR152 GPR42 HHLA2 ICAM3 IL10RA KASH5 KCNK5 KIR3DL1 KRT40 KRTAP10-3 KRTAP10-7 LEPROTL1 LMNA LRRC25 M6PR MGST3 MS4A3 MUC1 PEX12 PLD3 PTGES RETREG3 SCN3B SLC16A2 SLC18A1 SLC35C2 SLC41A3 SLC7A1 SLC7A14 SMIM3 SPINT1 STOM SUSD3 SYNE4 SYNPR TEX29 TFEC TMEM139 TMEM80 TMX2 VSIR WBP1
Entrez ID		3811	56935
HPRD ID		09226	17008
Ensembl ID		ENSG00000167633	ENSG00000166002
Uniprot IDs		P43629 Q5UCE2 Q6H2G3 Q8N6C9	A0A024R3A3 Q9NRQ5
PDB IDs		3VH8 3WUW 5B38 5B39 5T6Z 5T70 6V3J 7K80
Enriched GO Terms of Interacting Partners?
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