KIR3DL1 and BMP10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KIR3DL1	BMP10
Description		killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1	bone morphogenetic protein 10
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Region Extracellular Space Cytoplasm Cell Surface Z Disc
	Molecular Function	Amyloid-beta Binding Protein Binding HLA-B Specific Inhibitory MHC Class I Receptor Activity	Cytokine Activity Hormone Activity Protein Binding Growth Factor Activity Telethonin Binding Receptor Serine/threonine Kinase Binding
	Biological Process	Immune Response Natural Killer Cell Mediated Cytotoxicity	Kidney Development Cell Adhesion Adult Heart Development Negative Regulation Of Endothelial Cell Migration Positive Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Gene Expression Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Cell Growth Negative Regulation Of Cell Migration BMP Signaling Pathway Activin Receptor Signaling Pathway Sarcomere Organization Positive Regulation Of Transcription, DNA-templated Atrial Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Cell Development Regulation Of Cardiac Muscle Contraction Cardiac Muscle Cell Proliferation Positive Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Sarcomere Organization Heart Trabecula Formation Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction Positive Regulation Of Cartilage Development Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Signaling by BMP Molecules associated with elastic fibres
Drugs
Diseases
GWAS		Lymphocyte counts ( 32888494) Ulcerative colitis ( 28067908)	Chronic rhinosinusitis ( 33393196)
Interacting Genes		10 interacting genes: BMP10 CDK3 FPR1 HLA-B KIR2DS1 KIR2DS5 KIR3DS1 RPS6KB1 SMCO4 THSD7B	65 interacting genes: ACVR2A ACVR2B AP4B1 APOA5 AQP6 ARL13B BIK BMPR2 BSCL2 BSND C2orf42 CCDC70 CD33 CISD2 CLDN7 CNRIP1 COQ9 CREB3L1 DEXI EBP ERP29 FAM209A FCGR1A FCRL4 FFAR2 FKBP7 FNDC9 GGT6 GJB1 GPR152 GPX8 IL3RA JAGN1 KIR2DL3 KIR3DL1 KLRC1 LRRC25 LRRC4C MGST3 MRPS18B MS4A3 MTIF3 PLPP4 PNO1 RCN1 REEP4 SERINC3 SIT1 SLC10A1 SLC10A6 SLC35C2 SLC38A1 SLC4A1 SNRNP27 SPAG4 TCTA TMEM14B TMEM31 TMEM45B TMEM86B TMPRSS2 TNFSF14 TNFSF8 TSPAN31 VSIR
Entrez ID		3811	27302
HPRD ID		09226	09788
Ensembl ID		ENSG00000167633	ENSG00000163217
Uniprot IDs		P43629 Q5UCE2 Q6H2G3 Q8N6C9	O95393
PDB IDs		3VH8 3WUW 5B38 5B39 5T6Z 5T70 6V3J 7K80	6SF1 6SF3
Enriched GO Terms of Interacting Partners?
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