SFT2D2 and HIBADH

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SFT2D2	HIBADH
Description		SFT2 domain containing 2	3-hydroxyisobutyrate dehydrogenase
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Extracellular Exosome	Mitochondrion Mitochondrial Matrix
	Molecular Function	Molecular_function Protein Binding	Protein Binding 3-hydroxyisobutyrate Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor NADP Binding NAD Binding
	Biological Process	Biological_process Protein Transport Vesicle-mediated Transport	Valine Catabolic Process Branched-chain Amino Acid Catabolic Process
Pathways			Branched-chain amino acid catabolism
Drugs			NADH
Diseases
GWAS		Alzheimer's disease ( 30636644) LDL cholesterol levels in HIV infection ( 33109212)	Alcohol consumption (drinks per week) ( 30643258) Asthma ( 31959851) Diastolic blood pressure ( 27841878) General risk tolerance (MTAG) ( 30643258) Kidney stones ( 31729369) Lead levels in blood ( 25820613) Pulse pressure ( 27841878) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Systolic blood pressure ( 27841878)
Interacting Genes		29 interacting genes: AQP6 ATP5PF BNIP2 CREB3 ELOVL4 GPR152 HIBADH HSD17B11 HSD17B13 IFNGR2 INPP5K LMNA MOB2 NDRG4 PBX3 PLIN2 PLIN3 REEP2 REEP4 SLC10A1 SLC10A6 SLC30A8 STOM TAS2R5 TCP11X2 TIMM44 TMEM143 TMEM14B TMEM51	39 interacting genes: ADAM33 AGTRAP AIG1 AMELY AQP3 ASGR1 BRCA1 C2CD2L CDS2 CLEC2A CMTM7 CNIH2 COMT CTSA EFNA5 ERMP1 GOSR2 MAL NDUFB11 PAEP PLN PRAF2 PTCH1 RTP2 SCARB2 SEC22B SFT2D2 SNORC TFRC TM6SF2 TMEM14B TMEM222 TMEM60 TMEM86B TRIM63 UBIAD1 VAMP2 VAMP5 ZFPL1
Entrez ID		375035	11112
HPRD ID		14192	12238
Ensembl ID		ENSG00000213064	ENSG00000106049
Uniprot IDs		O95562	A0A024RA75 P31937
PDB IDs			2GF2 2I9P
Enriched GO Terms of Interacting Partners?
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