ITIH1 and PHAX

		ITIH1	PHAX
Description		inter-alpha-trypsin inhibitor heavy chain 1	phosphorylated adaptor for RNA export
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GO Annotations	Cellular Component	Extracellular Region Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle	Nucleus Nucleoplasm Centrosome Cytosol Cajal Body Neuronal Cell Body Ribonucleoprotein Complex
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Calcium Ion Binding	RNA Binding Protein Binding Toxic Substance Binding MRNA Cap Binding Complex Binding
	Biological Process	Negative Regulation Of Endopeptidase Activity Hyaluronan Metabolic Process	SnRNA Export From Nucleus Protein Transport RNA Stabilization
Pathways			snRNP Assembly RNA polymerase II transcribes snRNA genes
Drugs		Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972 19416921 33263727 31043756) Blood protein levels ( 29875488) Body mass index ( 25673413) Body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical surface area (MOSTest) ( 32665545) General cognitive ability ( 29844566) Glaucoma (primary open-angle) ( 25173105) Osteoarthritis (hip) ( 30374069) Pulse pressure ( 30578418) Schizophrenia ( 25056061 29483656 23974872) Schizophrenia, schizoaffective disorder or bipolar disorder ( 24166486) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 34021172 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)	Bipolar disorder ( 34099189) Colorectal cancer ( 30529582)
Interacting Genes		8 interacting genes: ARF4 ARIH2 CALR HSP90AA1 PHAX PIK3CA RBM15B SOX4	19 interacting genes: ASPSCR1 CDC42 GADD45G GRB7 ITIH1 MKNK1 NSFL1C OGT PDPK1 RAD23A RPS6KA1 STK3 TBCA TNFSF11 TULP3 UBXN2A VAV1 XPO1 ZWINT
Entrez ID		3697	51808
HPRD ID		00927	15122
Ensembl ID		ENSG00000055957	ENSG00000164902
Uniprot IDs		B7Z8B6 P19827	Q9H814
PDB IDs		6FPY 6FPZ	2XC7
Enriched GO Terms of Interacting Partners?
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