PHAX and MKNK1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		PHAX	MKNK1
Description		phosphorylated adaptor for RNA export	MAPK interacting serine/threonine kinase 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome Cytosol Cajal Body Neuronal Cell Body Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Binding Protein Binding Toxic Substance Binding MRNA Cap Binding Complex Binding	Protein Serine/threonine Kinase Activity Calmodulin-dependent Protein Kinase Activity Protein Binding Calmodulin Binding ATP Binding Calcium-dependent Protein Serine/threonine Kinase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	SnRNA Export From Nucleus Protein Transport RNA Stabilization	Regulation Of Translation Protein Phosphorylation Peptidyl-serine Phosphorylation Intracellular Signal Transduction Protein Autophosphorylation
Pathways		snRNP Assembly RNA polymerase II transcribes snRNA genes	Spry regulation of FGF signaling
Drugs			Fostamatinib
Diseases
GWAS		Bipolar disorder ( 34099189) Colorectal cancer ( 30529582)	Schizophrenia ( 26198764) Triglyceride levels ( 31170924)
Interacting Genes		19 interacting genes: ASPSCR1 CDC42 GADD45G GRB7 ITIH1 MKNK1 NSFL1C OGT PDPK1 RAD23A RPS6KA1 STK3 TBCA TNFSF11 TULP3 UBXN2A VAV1 XPO1 ZWINT	27 interacting genes: APP ATXN3 CREBBP CREM DDAH2 DNAJC7 EIF4E EIF4G1 EIF4G2 EIF4G3 FANCA HGS HIPK2 HSP90AB1 MAPK1 MAPK14 MAPK3 MBP PABPC4 PAK2 PHAX PLA2G4A PRKDC RCN3 SPRY2 TNIP2 UBE2D1
Entrez ID		51808	8569
HPRD ID		15122	09468
Ensembl ID		ENSG00000164902	ENSG00000079277
Uniprot IDs		Q9H814	A8K341 Q7Z319 Q9BUB5
PDB IDs		2XC7	2HW6 2Y9Q 5WVD
Enriched GO Terms of Interacting Partners?
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