ITIH1 and RBM15B

		ITIH1	RBM15B
Description		inter-alpha-trypsin inhibitor heavy chain 1	RNA binding motif protein 15B
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle	Nucleus Nuclear Envelope Nucleoplasm Nucleolus Nuclear Speck RNA N6-methyladenosine Methyltransferase Complex
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Calcium Ion Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	Negative Regulation Of Endopeptidase Activity Hyaluronan Metabolic Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Methylation MRNA Processing MRNA Export From Nucleus Nucleocytoplasmic Transport RNA Splicing Dosage Compensation By Inactivation Of X Chromosome Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs		Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972 19416921 33263727 31043756) Blood protein levels ( 29875488) Body mass index ( 25673413) Body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical surface area (MOSTest) ( 32665545) General cognitive ability ( 29844566) Glaucoma (primary open-angle) ( 25173105) Osteoarthritis (hip) ( 30374069) Pulse pressure ( 30578418) Schizophrenia ( 25056061 29483656 23974872) Schizophrenia, schizoaffective disorder or bipolar disorder ( 24166486) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 34021172 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)	Allergic disease (asthma, hay fever or eczema) ( 29679657) Apolipoprotein A1 levels ( 33730874)
Interacting Genes		8 interacting genes: ARF4 ARIH2 CALR HSP90AA1 PHAX PIK3CA RBM15B SOX4	14 interacting genes: AMT ATP6V0D2 CDC23 DVL3 EGR2 ERBB2 IMPDH2 ITIH1 NAV2 NXF1 PTEN SRPK2 TNNC1 TRIM54
Entrez ID		3697	29890
HPRD ID		00927	11486
Ensembl ID		ENSG00000055957	ENSG00000259956
Uniprot IDs		B7Z8B6 P19827	Q8NDT2
PDB IDs		6FPY 6FPZ
Enriched GO Terms of Interacting Partners?
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