TPRN and CLIC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TPRN	CLIC1
Description		taperin	chloride intracellular channel 1
Image
GO Annotations	Cellular Component	Stereocilium Stereocilium Base	Extracellular Space Nucleus Nuclear Envelope Cytoplasm Mitochondrion Plasma Membrane Brush Border Membrane Nuclear Membrane Vesicle Chloride Channel Complex Perinuclear Region Of Cytoplasm Extracellular Exosome Blood Microparticle
	Molecular Function	Molecular_function Protein Binding Phosphatase Binding	Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding Cadherin Binding
	Biological Process	Sensory Perception Of Sound Auditory Receptor Cell Stereocilium Organization Stereocilium Maintenance	Glutathione Metabolic Process Chloride Transport Signal Transduction Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Positive Regulation Of Osteoblast Differentiation Regulation Of Cell Cycle Regulation Of Mitochondrial Membrane Potential Platelet Aggregation
Pathways		Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs			Copper Artenimol
Diseases
GWAS		Obesity-related traits ( 23251661)	Adult body size ( 32376654) Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Inflammatory bowel disease ( 28067908) Mean platelet volume ( 27863252) Ulcerative colitis ( 28067908)
Interacting Genes		9 interacting genes: CLIC1 CLIC2 CLIC4 CLIC5 EPS8 MYO15B PPP1CA PPP1CC WHRN	24 interacting genes: AKAP9 ALOX5AP ATP5PB ATP6V0A1 ATP6V0C CPT1A DNAJC19 IKBKG LSM1 MEOX2 MYOC NHSL2 NTF4 NUP62 PCSK5 PRDX4 PSMD10 RPLP1 SUMO4 THRA TPRN TRAPPC2 ZNF184 ZNF302
Entrez ID		286262	1192
HPRD ID		12977	04188
Ensembl ID		ENSG00000176058	ENSG00000213719
Uniprot IDs		Q4KMQ1	O00299 Q53FB0 Q5SRT3
PDB IDs		6Y9Q	1K0M 1K0N 1K0O 1RK4 3O3T 3P8W 3P90 3QR6 3SWL 3TGZ 3UVH 4IQA 4JZQ 4K0G 4K0N
Enriched GO Terms of Interacting Partners?
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