TPRN and CLIC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TPRN	CLIC2
Description		taperin	chloride intracellular channel 2
Image
GO Annotations	Cellular Component	Stereocilium Stereocilium Base	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Chloride Channel Complex
	Molecular Function	Molecular_function Protein Binding Phosphatase Binding	Glutathione Transferase Activity Glutathione Peroxidase Activity Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding
	Biological Process	Sensory Perception Of Sound Auditory Receptor Cell Stereocilium Organization Stereocilium Maintenance	Glutathione Metabolic Process Chloride Transport Signal Transduction Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Positive Regulation Of Binding Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Oxidant Detoxification Chloride Transmembrane Transport
Pathways		Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea	Stimuli-sensing channels Ion homeostasis
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		9 interacting genes: CLIC1 CLIC2 CLIC4 CLIC5 EPS8 MYO15B PPP1CA PPP1CC WHRN	5 interacting genes: EP300 NEDD4 NEDD4L TPRN TRAPPC2
Entrez ID		286262	1193
HPRD ID		12977	02139
Ensembl ID		ENSG00000176058	ENSG00000155962
Uniprot IDs		Q4KMQ1	O15247
PDB IDs		6Y9Q	2PER 2R4V 2R5G
Enriched GO Terms of Interacting Partners?
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