TPRN and CLIC5

Number of citations of the paper that reports this interaction (PubMedID 26186194)
524

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		TPRN	CLIC5
Description		taperin	chloride intracellular channel 5
Image
GO Annotations	Cellular Component	Stereocilium Stereocilium Base	Golgi Apparatus Microtubule Organizing Center Cell Cortex Actin Cytoskeleton Apical Plasma Membrane Stereocilium Bundle Chloride Channel Complex Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding Phosphatase Binding	Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding
	Biological Process	Sensory Perception Of Sound Auditory Receptor Cell Stereocilium Organization Stereocilium Maintenance	Glutathione Metabolic Process Chloride Transport Female Pregnancy Visual Perception Sensory Perception Of Sound Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Response To Stimulus
Pathways		Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea	Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Blond vs. brown/black hair color ( 30531825) Blood protein levels ( 30072576 29875488) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Coronary artery disease in type 1 diabetes ( 32077919) Gout (normal type) ( 32238385) Heel bone mineral density ( 30598549) Intraocular pressure ( 29785010) Itch intensity from mosquito bite ( 28199695) LDL cholesterol levels in HIV infection ( 33109212) Mosquito bite size ( 28199695) Periodontal microbiota ( 22699663)
Interacting Genes		9 interacting genes: CLIC1 CLIC2 CLIC4 CLIC5 EPS8 MYO15B PPP1CA PPP1CC WHRN	9 interacting genes: ACTA1 ACTN1 EZR GSN IQGAP1 LAMTOR5 PTK7 SRPK1 TPRN
Entrez ID		286262	53405
HPRD ID		12977	06292
Ensembl ID		ENSG00000176058	ENSG00000112782
Uniprot IDs		Q4KMQ1	Q49AE1 Q53G01 Q9NZA1
PDB IDs		6Y9Q	6Y2H
Enriched GO Terms of Interacting Partners?
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