TPRN and CLIC4

Number of citations of the paper that reports this interaction (PubMedID 26186194)
524

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		TPRN	CLIC4
Description		taperin	chloride intracellular channel 4
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GO Annotations	Cellular Component	Stereocilium Stereocilium Base	Cytoplasm Mitochondrion Centrosome Cytosol Plasma Membrane Microvillus Cell-cell Junction Cell Surface Actin Cytoskeleton Microtubule Cytoskeleton Membrane Nuclear Matrix Midbody Cytoplasmic Vesicle Membrane Chloride Channel Complex Apical Part Of Cell Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding Phosphatase Binding	Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding
	Biological Process	Sensory Perception Of Sound Auditory Receptor Cell Stereocilium Organization Stereocilium Maintenance	Endothelial Cell Morphogenesis Chloride Transport Vacuolar Acidification Fertilization Cell Differentiation Keratinocyte Differentiation Negative Regulation Of Cell Migration Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Establishment Or Maintenance Of Apical/basal Cell Polarity Multicellular Organism Growth Branching Morphogenesis Of An Epithelial Tube Regulation Of Cytoskeleton Organization Retina Vasculature Morphogenesis In Camera-type Eye Cellular Response To Calcium Ion
Pathways		Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Heel bone mineral density ( 30598549) Height ( 20881960) Male-pattern baldness ( 28196072) Systolic blood pressure ( 29208002)
Interacting Genes		9 interacting genes: CLIC1 CLIC2 CLIC4 CLIC5 EPS8 MYO15B PPP1CA PPP1CC WHRN	7 interacting genes: ACTB DNM1 ERCC6 HSP90AB1 REL TPRN YWHAZ
Entrez ID		286262	25932
HPRD ID		12977	05943
Ensembl ID		ENSG00000176058	ENSG00000169504
Uniprot IDs		Q4KMQ1	Q6FIC5 Q9Y696
PDB IDs		6Y9Q	2AHE 2D2Z 3OQS
Enriched GO Terms of Interacting Partners?
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