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CCL26 and XCL1
Number of citations of the paper that reports this interaction (PubMedID
28381538
)
37
Data Source:
BioGRID
(pull down, pull down)
CCL26
XCL1
Description
C-C motif chemokine ligand 26
X-C motif chemokine ligand 1
Image
GO Annotations
Cellular Component
Extracellular Space
Extracellular Region
Extracellular Space
Molecular Function
Protein Binding
Chemokine Activity
CCR3 Chemokine Receptor Binding
CX3C Chemokine Receptor Binding
Receptor Ligand Activity
CCR Chemokine Receptor Binding
Protein Binding
Chemokine Activity
Chemokine Receptor Binding
Protein Homodimerization Activity
CCR Chemokine Receptor Binding
Biological Process
Positive Regulation Of Endothelial Cell Proliferation
Monocyte Chemotaxis
Chemotaxis
Inflammatory Response
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
T Cell Chemotaxis
Positive Regulation Of Cell Migration
Neutrophil Chemotaxis
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of GTPase Activity
Eosinophil Chemotaxis
Lymphocyte Chemotaxis
Positive Regulation Of Chemotaxis
Chemokine-mediated Signaling Pathway
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Interferon-gamma
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Positive Regulation Of T Cell Mediated Cytotoxicity
Monocyte Chemotaxis
Positive Regulation Of Leukocyte Chemotaxis
Negative Regulation Of T Cell Cytokine Production
Positive Regulation Of T Cell Cytokine Production
Negative Regulation Of T-helper 1 Type Immune Response
Inflammatory Response
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
Response To Virus
Positive Regulation Of T Cell Chemotaxis
Neutrophil Chemotaxis
Negative Regulation Of Interferon-gamma Production
Negative Regulation Of Interleukin-2 Production
Positive Regulation Of Interleukin-10 Production
Mature Natural Killer Cell Chemotaxis
Negative Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of GTPase Activity
Negative Regulation Of Transcription, DNA-templated
Lymphocyte Chemotaxis
Regulation Of Inflammatory Response
Release Of Sequestered Calcium Ion Into Cytosol
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Chemokine-mediated Signaling Pathway
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Interferon-gamma
Cellular Response To Interleukin-1
Cellular Response To Interleukin-4
Cellular Response To Tumor Necrosis Factor
Cellular Response To Transforming Growth Factor Beta Stimulus
Positive Regulation Of Transforming Growth Factor Beta Production
Positive Regulation Of Granzyme B Production
Positive Regulation Of Neutrophil Chemotaxis
Positive Regulation Of Thymocyte Migration
Positive Regulation Of Natural Killer Cell Chemotaxis
Positive Regulation Of Granzyme A Production
Negative Regulation Of T-helper 1 Cell Activation
Positive Regulation Of B Cell Chemotaxis
Positive Regulation Of T-helper 2 Cell Cytokine Production
Positive Regulation Of T-helper 1 Cell Cytokine Production
Positive Regulation Of Immunoglobulin Production In Mucosal Tissue
Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Positive Regulation Of CD8-positive, Alpha-beta T Cell Proliferation
Pathways
Chemokine receptors bind chemokines
G alpha (q) signalling events
Drugs
Diseases
GWAS
Carotid plaque burden (
28282560
)
Response to cognitive-behavioural therapy in major depressive disorder (
31123309
)
Blood protein levels (
30072576
29875488
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Metabolite levels (
23823483
)
Interacting Genes
24 interacting genes:
APP
C3orf52
CCL11
CCL13
CCL17
CCL2
CCL21
CCL28
CCL5
CCL8
CCR1
CCR3
CXCL10
CXCL11
CXCL12
CXCL14
CXCL17
CXCL9
PAX6
PF4
PF4V1
PPBP
XCL1
XCL2
21 interacting genes:
CCL11
CCL13
CCL21
CCL24
CCL26
CCL28
CCL5
CXCL10
CXCL11
CXCL12
CXCL14
CXCL17
CXCL2
CXCL9
FBLN5
KRTAP10-3
PF4
PF4V1
TNFSF18
VCAN
XCR1
Entrez ID
10344
6375
HPRD ID
05262
02595
Ensembl ID
ENSG00000006606
ENSG00000143184
Uniprot IDs
Q9Y258
P47992
PDB IDs
1G2S
1G2T
1J8I
1J9O
2HDM
2JP1
2N54
2NYZ
Enriched GO Terms of Interacting Partners
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