CCL26 and XCL2

Number of citations of the paper that reports this interaction (PubMedID 28381538)
37

Data Source:
BioGRID (pull down)

		CCL26	XCL2
Description		C-C motif chemokine ligand 26	X-C motif chemokine ligand 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Chemokine Activity CCR3 Chemokine Receptor Binding CX3C Chemokine Receptor Binding Receptor Ligand Activity CCR Chemokine Receptor Binding	Protein Binding Chemokine Activity CCR Chemokine Receptor Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Monocyte Chemotaxis Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling T Cell Chemotaxis Positive Regulation Of Cell Migration Neutrophil Chemotaxis Positive Regulation Of Actin Filament Polymerization Positive Regulation Of GTPase Activity Eosinophil Chemotaxis Lymphocyte Chemotaxis Positive Regulation Of Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Monocyte Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Blood Circulation Positive Regulation Of T Cell Chemotaxis Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor
Pathways			Chemokine receptors bind chemokines G alpha (q) signalling events
Drugs
Diseases
GWAS		Carotid plaque burden ( 28282560) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309)	Emphysema imaging phenotypes ( 26030696) Lung cancer ( 28604730) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		24 interacting genes: APP C3orf52 CCL11 CCL13 CCL17 CCL2 CCL21 CCL28 CCL5 CCL8 CCR1 CCR3 CXCL10 CXCL11 CXCL12 CXCL14 CXCL17 CXCL9 PAX6 PF4 PF4V1 PPBP XCL1 XCL2	19 interacting genes: CCL2 CCL20 CCL21 CCL26 CCL28 CCL5 CCL7 CCL8 CXCL12 CXCL17 CXCL2 CXCL3 CXCL5 KRTAP1-3 KRTAP10-9 NOTCH2NLA PF4 PF4V1 XCR1
Entrez ID		10344	6846
HPRD ID		05262	05317
Ensembl ID		ENSG00000006606	ENSG00000143185
Uniprot IDs		Q9Y258	Q9UBD3
PDB IDs		1G2S 1G2T
Enriched GO Terms of Interacting Partners?
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