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CCL26 and PF4
Number of citations of the paper that reports this interaction (PubMedID
28381538
)
37
Data Source:
BioGRID
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CCL26
PF4
Description
C-C motif chemokine ligand 26
platelet factor 4
Image
GO Annotations
Cellular Component
Extracellular Space
Extracellular Region
Extracellular Space
Cytoplasm
Symbiont-containing Vacuole Membrane
Platelet Alpha Granule Lumen
Collagen-containing Extracellular Matrix
Molecular Function
Protein Binding
Chemokine Activity
CCR3 Chemokine Receptor Binding
CX3C Chemokine Receptor Binding
Receptor Ligand Activity
CCR Chemokine Receptor Binding
Protein Binding
Chemokine Activity
Heparin Binding
CXCR Chemokine Receptor Binding
CXCR3 Chemokine Receptor Binding
Biological Process
Positive Regulation Of Endothelial Cell Proliferation
Monocyte Chemotaxis
Chemotaxis
Inflammatory Response
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
T Cell Chemotaxis
Positive Regulation Of Cell Migration
Neutrophil Chemotaxis
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of GTPase Activity
Eosinophil Chemotaxis
Lymphocyte Chemotaxis
Positive Regulation Of Chemotaxis
Chemokine-mediated Signaling Pathway
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Interferon-gamma
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Inflammatory Response
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Gene Expression
Positive Regulation Of Macrophage Derived Foam Cell Differentiation
Negative Regulation Of Angiogenesis
Cytokine-mediated Signaling Pathway
Platelet Activation
Neutrophil Chemotaxis
Leukocyte Chemotaxis
Positive Regulation Of Tumor Necrosis Factor Production
Regulation Of Cell Population Proliferation
Defense Response To Protozoan
Negative Regulation Of MHC Class II Biosynthetic Process
Positive Regulation Of Macrophage Differentiation
Negative Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Killing By Host Of Symbiont Cells
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Chemokine-mediated Signaling Pathway
Cellular Response To Lipopolysaccharide
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
Platelet degranulation
Common Pathway of Fibrin Clot Formation
Cell surface interactions at the vascular wall
Chemokine receptors bind chemokines
G alpha (i) signalling events
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Drotrecogin alfa
Heparin
Diseases
GWAS
Carotid plaque burden (
28282560
)
Response to cognitive-behavioural therapy in major depressive disorder (
31123309
)
Inflammatory bowel disease (
23128233
)
Metabolite levels (
22916037
)
Serum metabolite levels (
31636271
)
Serum metabolite levels (CMS) (
31636271
)
Interacting Genes
24 interacting genes:
APP
C3orf52
CCL11
CCL13
CCL17
CCL2
CCL21
CCL28
CCL5
CCL8
CCR1
CCR3
CXCL10
CXCL11
CXCL12
CXCL14
CXCL17
CXCL9
PAX6
PF4
PF4V1
PPBP
XCL1
XCL2
28 interacting genes:
CCL11
CCL13
CCL2
CCL20
CCL21
CCL25
CCL26
CCL28
CCL5
CXCL10
CXCL11
CXCL12
CXCL14
CXCL17
CXCL2
CXCL6
CXCL8
CXCL9
CXCR3
FGF2
LDLR
PROC
SDC2
SRGN
THBD
VCAN
XCL1
XCL2
Entrez ID
10344
5196
HPRD ID
05262
01426
Ensembl ID
ENSG00000006606
ENSG00000163737
Uniprot IDs
Q9Y258
P02776
PDB IDs
1G2S
1G2T
1DN3
1F9Q
1F9R
1F9S
1PFM
1PFN
1RHP
4R9W
4R9Y
4RAU
Enriched GO Terms of Interacting Partners
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