CA12 and CUX1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		CA12	CUX1
Gene Name		carbonic anhydrase XII	cut-like homeobox 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Nucleus Cytosol Integral Component Of Golgi Membrane
	Molecular Function	Carbonate Dehydratase Activity Zinc Ion Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Sequence-specific DNA Binding
	Biological Process	One-carbon Metabolic Process Bicarbonate Transport Small Molecule Metabolic Process Chloride Ion Homeostasis	Negative Regulation Of Transcription From RNA Polymerase II Promoter Kidney Development Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Intra-Golgi Vesicle-mediated Transport Multicellular Organismal Development Lung Development Auditory Receptor Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Dendrite Morphogenesis
Pathways		Reversible hydration of carbon dioxide	Signaling by FGFR in disease Signaling by FGFR1 mutants Signaling by FGFR mutants Signaling by FGFR1 fusion mutants
Drugs		Benzthiazide Hydroflumethiazide Zonisamide Hydrochlorothiazide Ellagic Acid
Diseases
GWAS			Response to antidepressants ( 22584459)
Protein-Protein Interactions		10 interactors: ATP5C1 CUX1 DAXX KATNBL1 LGALS7 MAPK6 MRPL9 RDH11 SGSM2 TOE1	20 interactors: BIN1 CA12 CCNA1 CDC25A CDK1 CDK7 CREBBP CTSL CYTH2 EHMT2 ELAC2 GOLGA5 HMGB1 KAT2B MAX RB1 RECQL5 SATB1 SDC3 TLE4
Entrez ID		771	1523
HPRD ID		04464	00295
Ensembl ID			ENSG00000257923
Uniprot IDs		B3KUB4 O43570	P39880 Q13948 Q3LIA3
PDB IDs		1JCZ 1JD0 4HT2
Enriched GO Terms of Interacting Partners?			Regulation Of Transcription From RNA Polymerase II Promoter Organelle Organization G1/S Transition Of Mitotic Cell Cycle Chromatin Modification Negative Regulation Of Gene Expression Chromosome Organization Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cell Division Cell Cycle Process Chromatin Organization Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription From RNA Polymerase II Promoter N-terminal Peptidyl-lysine Acetylation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G2/M Transition Of Mitotic Cell Cycle Viral Process Mitotic Nuclear Division Regulation Of Cell Cycle Cell Cycle Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Histone Modification Mitotic Cell Cycle Process Chromatin Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Protein Kinase Activity Negative Regulation Of RNA Biosynthetic Process Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Kinase Activity Regulation Of Nucleic Acid-templated Transcription Protein Localization To Chromosome, Centromeric Region Regulation Of RNA Biosynthetic Process N-terminal Protein Amino Acid Acetylation Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Catalytic Activity Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Apoptotic Process Regulation Of Gene Expression Programmed Cell Death Regulation Of Nitrogen Compound Metabolic Process Cell Death
Tagcloud ?		adenocarcinoma adenosquamous bilateral cea cervix chemoradiotherapy ck5 ck7 concurrent dissection distant hysterectomy intracolposcopic irregular lymphadenectomy nodes oophorectomy papillary pelvic poorer postoperative ppsc pure rarely salpingo serous unpredictable vaginal woman	accumulated activators ancillary base burden cut ectopic excision framework haploinsufficiency homeobox implicated isoform isoforms mechanistic opposite paradoxically progression promotes protection reconcile repressors supports suppression transgenic tumorigenesis tumour whereby yet
Tagcloud (Difference) ?		adenocarcinoma adenosquamous bilateral cea cervix chemoradiotherapy ck5 ck7 concurrent dissection distant hysterectomy intracolposcopic irregular lymphadenectomy nodes oophorectomy papillary pelvic poorer postoperative ppsc pure rarely salpingo serous unpredictable vaginal woman	accumulated activators ancillary base burden cut ectopic excision framework haploinsufficiency homeobox implicated isoform isoforms mechanistic opposite paradoxically progression promotes protection reconcile repressors supports suppression transgenic tumorigenesis tumour whereby yet
Tagcloud (Intersection) ?